[HTML][HTML] Progress towards the development of a universal influenza vaccine

WC Wang, EE Sayedahmed, S Sambhara, SK Mittal - Viruses, 2022 - mdpi.com
Influenza viruses are responsible for millions of cases globally and significantly threaten
public health. Since pandemic and zoonotic influenza viruses have emerged in the last 20 …

The race toward a universal influenza vaccine: Front runners and the future directions

L Hu, G Lao, R Liu, J Feng, F Long, T Peng - Antiviral Research, 2023 - Elsevier
Influenza virus is the pathogen of influenza (flu) and millions of people suffer from the
infection worldwide, posing a significant health risk. The current influenza vaccines induce …

[HTML][HTML] Novel platforms for the development of a universal influenza vaccine

A Kumar, TS Meldgaard, S Bertholet - Frontiers in immunology, 2018 - frontiersin.org
Despite advancements in immunotherapeutic approaches, influenza continues to cause
severe illness, particularly among immunocompromised individuals, young children, and …

[HTML][HTML] Broadly protective strategies against influenza viruses: universal vaccines and therapeutics

OA Vogel, B Manicassamy - Frontiers in microbiology, 2020 - frontiersin.org
Influenza virus is a respiratory pathogen that can cause disease in humans, with symptoms
ranging from mild to life-threatening. The vast majority of influenza virus infections in …

[HTML][HTML] The next generation of influenza vaccines: Towards a universal solution

CLD McMillan, PR Young, D Watterson, KJ Chappell - Vaccines, 2021 - mdpi.com
Influenza viruses remain a constant burden in humans, causing millions of infections and
hundreds of thousands of deaths each year. Current influenza virus vaccine modalities …

Universal influenza vaccines: Shifting to better vaccines

FB Scorza, V Tsvetnitsky, JJ Donnelly - Vaccine, 2016 - Elsevier
Influenza virus causes acute upper and lower respiratory infections and is the most likely,
among known pathogens, to cause a large epidemic in humans. Influenza virus mutates …

Universal influenza vaccines, science fiction or soon reality?

RD de Vries, AF Altenburg… - Expert review of …, 2015 - Taylor & Francis
Currently used influenza vaccines are only effective when the vaccine strains match the
epidemic strains antigenically. To this end, seasonal influenza vaccines must be updated …

Vaccine approaches conferring cross-protection against influenza viruses

SV Vemula, EE Sayedahmed, S Sambhara… - Expert review of …, 2017 - Taylor & Francis
Introduction: Annual vaccination is one of the most efficient and cost-effective strategies to
prevent and control influenza epidemics. Most of the currently available influenza vaccines …

Is it possible to develop a “universal” influenza virus vaccine? Potential target antigens and critical aspects for a universal influenza vaccine

F Krammer, A García-Sastre… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Influenza viruses cause seasonal epidemics as well as pandemics and are a significant
concern for human health. Current influenza virus vaccines show efficacy when they are …

[HTML][HTML] Developing universal influenza vaccines: hitting the nail, not just on the head

LCM Wiersma, GF Rimmelzwaan, RD De Vries - Vaccines, 2015 - mdpi.com
Influenza viruses have a huge impact on public health. Current influenza vaccines need to
be updated annually and protect poorly against antigenic drift variants or novel emerging …