Although prematurity and hypoxic–ischaemic injury are well‐recognized contributors to the
pathogenesis of cerebral palsy (CP), as many as one‐third of children with CP may lack …

Cohort-based whole exome and whole genome sequencing and copy number variant
(CNV) studies have identified genetic etiologies for a sizable proportion of patients with …

Cerebral palsy (CP) is heterogeneous with different clinical types, comorbidities, brain
imaging patterns, causes, and now also heterogeneous underlying genetic variants. Few …

Cerebral palsy is the most prevalent physical disability in children; however, its inherent
molecular mechanisms remain unclear. In the present study, we performed in-depth clinical …

Objective Cerebral palsy is a common, heterogeneous neurodevelopmental disorder that
causes movement and postural disabilities. Recent studies have suggested genetic …

DIAGNOSIS OF CEREBRAL PALSY The diagnosis of CP relies on a combination of
neurologic assessment, neuroimaging findings, and recognition of clinical risk factors …

High throughput sequencing is discovering many likely causative genetic variants in
individuals with cerebral palsy. Some investigators have suggested that this changes the …

Cerebral palsy—the most common physical disability of childhood—is a clinical diagnosis
encompassing a heterogeneous group of neurodevelopmental disorders that cause …

We performed whole-genome sequencing (WGS) in 327 children with cerebral palsy (CP)
and their biological parents. We classified 37 of 327 (11.3%) children as having …

Cerebral palsy is a sporadic disorder with multiple likely aetiologies, but frequently
considered to be caused by birth asphyxia. Genetic investigations are rarely performed in …