D-dimer testing: A narrative review

L Wauthier, J Favresse, M Hardy, J Douxfils… - Advances in clinical …, 2023 - Elsevier
D-dimer containing species are soluble fibrin degradation products derived from plasmin-
mediated degradation of cross-linked fibrin, ie,'D-dimer'. D-dimer can hence be considered a …

D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications

J Favresse, G Lippi, PM Roy, B Chatelain… - Critical reviews in …, 2018 - Taylor & Francis
D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …

d-Dimer Testing in Laboratory Practice

A Tripodi - Clinical chemistry, 2011 - academic.oup.com
BACKGROUND d-dimer is a reliable and sensitive index of fibrin deposition and
stabilization. As such, its presence in plasma should be indicative of thrombus formation …

Harmonisation of D-dimer—A call for action

C Longstaff, D Adcock, JD Olson… - Thrombosis …, 2016 - thrombosisresearch.com
D-dimer is a stable, terminal product of fibrin degradation in plasma. In the 1970s, Gaffney
and colleagues introduced the concept of D-dimer measurement as a biomarker of …

A test in context: D-dimer

JI Weitz, JC Fredenburgh, JW Eikelboom - Journal of the American College …, 2017 - jacc.org
D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

The current role and future prospects of D-dimer biomarker

AY Soomro, A Guerchicoff, DJ Nichols… - European Heart …, 2016 - academic.oup.com
D-dimers have been discovered as by-products of fibrinolysis. In situations where the
fundamental pathology is associated with increased thrombolytic activity, D-dimer assays …

D-dimer testing within the routine clinical chemistry profile

TC Vukovich, A Hamwi, C Bieglmayer - Clinical chemistry, 1998 - academic.oup.com
D-Dimer is the term for any of a variety of split products that are derived from fibrin fibrils by
the action of the fibrinolytic enzyme plasmin. They occur in the circulation in a wide range of …

Advances in D-dimer testing: progress in harmonization of clinical assays and innovative detection methods

R Zhao, M Li, P Xiao, D Song, H Li - Analytical and Bioanalytical Chemistry, 2024 - Springer
The D-dimer is a sensitive indicator of coagulation and fibrinolysis activation, especially
valuable as a biomarker of intravascular thrombosis. Measurement of plasma D-dimer levels …

The D‐dimer assay

ED Johnson, JC Schell… - American journal of …, 2019 - Wiley Online Library
D‐dimer is an indirect marker of fibrinolysis and fibrin turnover; this molecule exhibits unique
properties as a biological marker of hemostatic abnormalities as well as an indicator of …

[HTML][HTML] How we manage a high D-dimer

M Franchini, D Focosi, MP Pezzo, PM Mannucci - Haematologica, 2024 - ncbi.nlm.nih.gov
D-dimer, a soluble fibrin degradation product that originates from plasmin-induced
degradation of cross-linked fibrin, is an important biomarker of coagulation activation and …