[HTML][HTML] Interleukin 22 in liver injury, inflammation and cancer

Y Wu, J Min, C Ge, J Shu, D Tian, Y Yuan… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Interleukin 22 (IL-22), a member of the IL-10 cytokine family and is an emerging
CD4+ Th cytokine that plays an important role in anti-microbial defense, homeostasis and …

Role of interleukin-22 in liver diseases

C Pan, J Tang, X Wang, F Wu, J Ge, F Chen - Inflammation Research, 2014 - Springer
Abstract Introduction Interleukin (IL)-22, originally referred to as IL-TIF for IL-10-related T cell-
derived inducible factor, is a member of the IL-10-like cytokine family. IL-22 is highly …

The interleukin-20 cytokine family in liver disease

E Caparrós, R Francés - Frontiers in Immunology, 2018 - frontiersin.org
The three main causes of inflammation and chronic injury in the liver are viral hepatitis,
alcohol consumption, and non-alcoholic steatohepatitis, all of which can lead to liver fibrosis …

Type 3 cytokines in liver fibrosis and liver cancer

MF Molina, MN Abdelnabi, T Fabre, NH Shoukry - Cytokine, 2019 - Elsevier
The type 3 cytokines IL-17 and IL-22 play a crucial, well synchronized physiological role in
wound healing and repairing tissue damage due to infections or injury at barrier surfaces …

How Does Interleukin‐22 Mediate Liver Regeneration and Prevent Injury and Fibrosis?

MB Khawar, F Azam, N Sheikh… - Journal of Immunology …, 2016 - Wiley Online Library
Interleukin‐22 (IL‐22) is a pluripotent T cell‐derived cytokine which is a member of IL‐10
cytokine family. It is the only interleukin produced by immune cells but does not target …

Role of Interleukin-22 in chronic liver injury

RF Carmo, MSM Cavalcanti, P Moura - Cytokine, 2017 - Elsevier
Liver fibrosis is the result of an exacerbated wound-healing response associated with
chronic liver injury. Advanced liver fibrosis results in cirrhosis, liver failure, and portal …

Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

LA Zenewicz, GD Yancopoulos, DM Valenzuela… - Immunity, 2007 - cell.com
Summary The cytokine interleukin-22 (IL-22) is primarily expressed by T helper 17 (Th17)
CD4+ T cells and is highly upregulated during chronic inflammatory diseases. IL-22 receptor …

Hepatoprotective effects of IL-22 on fulminant hepatic failure induced by d-galactosamine and lipopolysaccharide in mice

W Xing, M Zou, S Liu, T Xu, J Gao, J Wang, D Xu - Cytokine, 2011 - Elsevier
Interleukin-22 (IL-22), a member of the IL-10 cytokine family that is produced by activated
Th22, Th1 and Th17 cells as well as natural killer cells, plays an important role in increase of …

A protective function of IL-22BP in ischemia reperfusion and acetaminophen-induced liver injury

D Kleinschmidt, AD Giannou, HM McGee… - The Journal of …, 2017 - journals.aai.org
Acute liver injury can be secondary to a variety of causes, including infections, intoxication,
and ischemia. All of these insults induce hepatocyte death and subsequent inflammation …

[HTML][HTML] Protective and pathological properties of IL-22 in liver disease: implications for viral hepatitis

MA Cobleigh, MD Robek - The American journal of pathology, 2013 - Elsevier
Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection affect> 500 million
people worldwide and are significant causes of liver cirrhosis and hepatocellular carcinoma …