Sunitinib in patients with metastatic renal cell carcinoma

RJ Motzer, BI Rini, RM Bukowski, BD Curti, DJ George… - Jama, 2006 - jamanetwork.com
… to treatment with sunitinib. This patient had clear-cell RCC metastatic to the mediastinum
and lung with symptoms of episodic dyspnea. Following 28 days of sunitinib therapy, the …

Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial

ME Gore, C Szczylik, C Porta, S Bracarda… - The lancet …, 2009 - thelancet.com
… The association between adverse events and sunitinib therapy was assessed by the
investigator. Patients who discontinued therapy because of an adverse event continued follow-up …

Sunitinib: ten years of successful clinical use and study in advanced renal cell carcinoma

RJ Motzer, B Escudier, A Gannon, RA Figlin - The oncologist, 2017 - academic.oup.com
… of the era of targeted therapy, and specifically the approval of sunitinib, it is worthwhile to …
to the study of sunitinib. We present the key trials and data for sunitinib that established it as a …

[HTML][HTML] Sunitinib therapy for metastatic renal cell carcinoma: recommendations for management of side effects

C Kollmannsberger, D Soulieres, R Wong… - Canadian Urological …, 2007 - ncbi.nlm.nih.gov
… of sunitinib. Fatigue may be partly related to the development of hypothyroidism during sunitinib
therapy … Hypertension can be treated with standard antihypertensive therapy and rarely …

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

RJ Motzer, TE Hutson, P Tomczak… - … England Journal of …, 2007 - Mass Medical Soc
… We enrolled 750 patients with previously untreated, metastatic renal-cell carcinoma in a
multicenter, randomized, phase 3 trial to receive either repeated 6-week cycles of sunitinib (at a …

Sequential therapy with sorafenib and sunitinib in renal cell carcinoma

AZ Dudek, J Zolnierek, A Dham, BR Lindgren… - Cancer, 2009 - Wiley Online Library
… with histologically confirmed renal cell carcinoma. All renal cell carcinoma patients were
screened for … toxicity after receiving either sorafenib or sunitinib, and then these patients were …

Sunitinib efficacy against advanced renal cell carcinoma

RJ Motzer, MD Michaelson, J Rosenberg… - The Journal of …, 2007 - Elsevier
therapy with sunitinib in patients with metastatic RCC. The tumor response and durability of
response to sunitinib … As second line therapy, the sunitinib response rate was 2 to 3 times …

Management of side effects associated with sunitinib therapy for patients with renal cell carcinoma

A Schwandt, LS Wood, B Rini… - OncoTargets and therapy, 2009 - Taylor & Francis
Sunitinib is an oral tyrosine kinase inhibitor which interferes … sunitinib therapy with emphasis
on establishing effective patient education for anticipation and early management of therapy-…

[HTML][HTML] Sunitinib resistance in renal cell carcinoma

C Morais - Journal of Kidney Cancer and VHL, 2014 - ncbi.nlm.nih.gov
therapies introduced since 2006, sunitinib has carved its way to become the most commonly
used first-line therapy for the treatment of metastatic renal cell carcinoma (… to sunitinib and …

Experience with sunitinib in the treatment of metastatic renal cell carcinoma

M Schmidinger, J Larkin… - Therapeutic advances in …, 2012 - journals.sagepub.com
sunitinib in mRCC, with an emphasis on real-world data, and utilize clinical case studies to
examine the successful implementation of therapy … effects associated with sunitinib therapy, …