In this study, endothelial cell-mediated clot retraction was supported by fibrin generated from
several purified fractions of plasma fibrinogen, purified proteolytic fragments of plasma …

Fibrinogen is a plasma protein that interacts with integrin αIIbβ3 to mediate a variety of
platelet responses including adhesion, aggregation, and clot retraction. Three sites on …

Platelet integrin α IIb β 3 (GPIIb-IIIa) plays important roles in platelet-mediated clot retraction.
However, little is known about the mechanisms of clot retraction mediated by nucleated …

The interactions of platelets with fibrinogen mediate a variety of responses including
adhesion, platelet aggregation, and fibrin clot retraction. Whereas it was assumed that …

We have analyzed tyrosine phosphorylation associated with retraction of the fibrin clot by
washed platelets in purified fibrinogen. Retraction was dependent on integrin α IIb β 3 …

Fibrinogen mediates the processes of platelet aggregation and clot retraction. Previous
studies have demonstrated that fibrinogen binding to the platelet receptor αβ requires the C …

Fibrin clot retraction may be important in resolution of thrombi and, in platelets, is mediated
by integrin α IIb β 3 (GPIIb-llla). Nucleated cells that lack α llb β 3 can retract fibrin clots, and …

Dear Sir, Platelet-mediated clot retraction is necessary for the consolidation of a platelet
thrombus by making it less susceptible to fibrinolysis. In vitro, clot retraction is completely …

The rate of clot retraction in platelet-rich plasma was decreased by synthetic peptide
analogues of fibrinogen and monoclonal antibodies each of which bind to the platelet …

Retraction of the blood clot by nucleated cells contributes both to hemostasis and to tissue
remodeling. Although plasma fibronectin (FN) is a key component of the clot, its role in clot …