Iron metabolism in obesity: how interaction between homoeostatic mechanisms can interfere with their original purpose. Part I: underlying homoeostatic mechanisms …

C Becker, M Orozco, NW Solomons… - Journal of Trace Elements …, 2015 - Elsevier
Adipose tissue plasticity mediated by inflammation is an important evolutionary achievement
to survive seasonal climate changes. It permits to store excessive calories and to release …

Iron, glucose and fat metabolism and obesity: an intertwined relationship

C Hilton, R Sabaratnam, H Drakesmith… - International Journal of …, 2023 - nature.com
A bidirectional relationship exists between adipose tissue metabolism and iron regulation.
Total body fat, fat distribution and exercise influence iron status and components of the iron …

Iron: The silent culprit in your adipose tissue

JM Moreno‐Navarrete, JM Fernández‐Real - Obesity Reviews, 2024 - Wiley Online Library
Iron plays a vital role in essential biological processes and requires precise regulation within
the body. Dysregulation of iron homeostasis, characterized by increased serum ferritin levels …

Iron metabolism in obesity: how interaction between homoeostatic mechanisms can interfere with their original purpose. Part II: epidemiological and historic aspects of …

C Becker, M Orozco, NW Solomons… - Journal of Trace Elements …, 2015 - Elsevier
The change from a mainly vegetarian fare to meat consumption went along with brain
growth and increased insulin resistance to improve brain's glucose supply. Meat …

Mutual interaction between iron homeostasis and obesity pathogenesis

AA Nikonorov, MG Skalnaya, AA Tinkov… - Journal of trace elements …, 2015 - Elsevier
Obesity is identified as an important medical problem. One of the pathologic conditions
observed in obesity is systemic iron deficiency and hypoferremia. Along with a large number …

Iron deficiency and obesity: the contribution of inflammation and diminished iron absorption

JP McClung, JP Karl - Nutrition reviews, 2009 - academic.oup.com
Poor iron status affects billions of people worldwide. The prevalence of obesity continues to
rise in both developed and developing nations. An association between iron status and …

Iron in obesity. An ancient micronutrient for a modern disease

C Zafon, A Lecube, R Simo - Obesity reviews, 2010 - Wiley Online Library
Iron is a necessary constituent of several macromolecules involved in cell metabolism, but,
at the same time, it could be a potentially dangerous element. For this reason iron balance …

Obesity as an emerging risk factor for iron deficiency

E Aigner, A Feldman, C Datz - Nutrients, 2014 - mdpi.com
Iron homeostasis is affected by obesity and obesity-related insulin resistance in a many-
facetted fashion. On one hand, iron deficiency and anemia are frequent findings in subjects …

The orchestration of body iron intake: how and where do enterocytes receive their cues?

DM Frazer, GJ Anderson - Blood cells, molecules, and diseases, 2003 - Elsevier
Our understanding of how iron transverses the intestinal epithelium has improved greatly in
recent years, although the mechanism by which body iron demands regulate this process …

[HTML][HTML] Iron homeostasis and energy metabolism in obesity

SL Kim, S Shin, SJ Yang - Clinical nutrition research, 2022 - ncbi.nlm.nih.gov
Iron plays a role in energy metabolism as a component of vital enzymes and electron
transport chains (ETCs) for adenosine triphosphate (ATP) synthesis. The tricarboxylic acid …