Diverse applications of nitrones for the synthesis of heterocyclic compounds

LL Anderson - Asian Journal of Organic Chemistry, 2016 - Wiley Online Library
Although best known for their [3+ 2]‐dipolar cycloaddition reactivity and use in the
preparation of isoxazolines and isoxazolidines, nitrones are versatile reagents that undergo …

Part I: Nitroalkenes in the synthesis of heterocyclic compounds

AZ Halimehjani, INN Namboothiri, SE Hooshmand - RSC Advances, 2014 - pubs.rsc.org
The applications of nitroalkenes in the synthesis of three-to five-membered O, N and S-
heterocycles, including natural products are investigated in this review. These heterocyclic …

1, 3-Dipolar cycloaddition of nitrones: synthesis of multisubstituted, diverse range of heterocyclic compounds

S Thakur, A Das, T Das - New Journal of Chemistry, 2021 - pubs.rsc.org
Cycloadditions are known to be one of the most abundant, versatile and valuable classes of
chemical reactions. Among various efficient chemical processes, cycloaddition is an …

A New Synthesis of Highly Functional Nitrones through a Nitrosoketene Intermediate and Their Use for the Stereoselective Synthesis of Amino Acids

N Katagiri, H Sato, A Kurimoto, M Okada… - The Journal of …, 1994 - ACS Publications
Reaction of 5-isonitroso-2, 2-dimethyl-l, 3-dioxane-4, 6-dione with various ketones under
reflux in toluene gives 3-oxazolin-5-one 3-oxides (cyclic nitrones) via a nitrosoketene …

Part II: nitroalkenes in the synthesis of heterocyclic compounds

AZ Halimehjani, INN Namboothiri, SE Hooshmand - RSC Advances, 2014 - pubs.rsc.org
This part (part II) is devoted to 6-membered heterocycles that are synthesized from
nitroalkenes as the key substrates. These compounds can be simply accessible to form …

[3+ 2] Dipolar cycloadditions of cyclic nitrones with alkenes

A Brandi, F Cardona, S Cicchi, FM Cordero… - Organic …, 2004 - Wiley Online Library
Abstract The chapter describes the 1, 3‐dipolar cycloadditions of cyclic nitrones with alkenes
and surveys the literature from 1985 to 2014. In addition to comprehensive coverage of the …

Regiochemistry in the intramolecular cycloadditions of substituted 5-alkenyl and 6-alkenyl nitrones

SW Baldwin, JD Wilson, J Aube - The Journal of Organic …, 1985 - ACS Publications
A series of 5-alkenyland 6-alkenyl aldehydes bearing aryl and ester functionality on the
alkene and with and without 1, 3-dioxolane substitution at the 3 position has been prepared …

Recent developments in nitrone chemistry: some novel transformations

J Yang - Synlett, 2012 - thieme-connect.com
Despite the long history of nitrone chemistry, novel transformations of nitrones continue to be
discovered. This article describes some recent breakthroughs in the development of new …

Isoxazolines from nitro compounds: synthesis and applications

INN Namboothiri, N Rastogi - Synthesis of heterocycles via cycloadditions I, 2008 - Springer
This paper reviews the construction of isoxazoline rings via 1, 3-dipolar cycloaddition of
nitrile oxides or nitronates, including silyl nitronates, generated from nitroalkanes, with …

Nitroalkenes in the synthesis of carbocyclic compounds

AZ Halimehjani, INN Namboothiri, SE Hooshmand - RSC Advances, 2014 - pubs.rsc.org
The applications of nitroalkenes in the synthesis of small, common and medium ring
carbocycles, including natural products are investigated in this review. These carbocyclic …