Q Dong, KR Smith, DG Oldenburg, M Shapiro… - MBio, 2018 - Am Soc Microbiol
Misincorporation of uracil or spontaneous cytidine deamination is a common mutagenic insult to DNA. Herpesviruses encode a viral uracil-DNA glycosylase (vUNG) and a viral …
Longitudinal deep sequencing of viruses can provide detailed information about intra-host evolutionary dynamics, including how viruses interact with and transmit between hosts …
LN Akhtar, CD Bowen, DW Renner, U Pandey… - bioRxiv, 2018 - biorxiv.org
More than 14,000 neonates are infected with herpes simplex virus (HSV) annually. Approximately half display manifestations limited to the skin, eyes, or mouth (SEM disease) …
Human cytomegalovirus (HCMV) is a β-herpesvirus that causes complications in immuno- compromised individuals and is the leading infectious cause of birth defects. The HCMV …
Misincorporation of uracil or spontaneous cytidine deamination is a common mutagenic insult to DNA. Herpesviruses encode a viral uracil-DNA glycosylase (vUNG) and a viral …
NM Suárez, KG Musonda, E Escriva, M Njenga… - bioRxiv, 2018 - biorxiv.org
Background In developed countries, human cytomegalovirus, HCMV, is a major pathogen in congenitally infected people and immunocompromised individuals, where multiple-strain …
Human cytomegalovirus (HCMV) is a ubiquitous human pathogen and contains double stranded DNA genome with approximately 230 kbp. Molecular genomic studies of HCMV …
Significant genetic variability exists between strains of murine cytomegalovirus (MCMV), which can have profound impacts on the function of immunomodulatory genes. Analysis of a …
CD Bowen, H Paavilainen, DW Renner, J Palomäki… - bioRxiv, 2018 - biorxiv.org
A majority of adults in Finland are seropositive carriers of herpes simplex viruses (HSV). Infection occurs at epithelial or mucosal surfaces, after which virions enter innervating nerve …