Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin

M Telford, A Navarro, G Santpere - Scientific Reports, 2018 - nature.com
Human herpesviruses 6-A and-B (HHV-6A, HHV-6B) are ubiquitous in human populations
worldwide. These viruses have been associated with several diseases such as multiple …

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

AL Greninger, GM Knudsen, P Roychoudhury… - BMC genomics, 2018 - Springer
Background Human herpesvirus-6A and-6B (HHV-6) are betaherpesviruses that reach>
90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 …

Copy number heterogeneity, large origin tandem repeats, and interspecies recombination in human herpesvirus 6A (HHV-6A) and HHV-6B reference strains

AL Greninger, P Roychoudhury, N Makhsous… - Journal of …, 2018 - Am Soc Microbiol
Quantitative PCR is a diagnostic pillar for clinical virology testing, and reference materials
are necessary for accurate, comparable quantitation between clinical laboratories. Accurate …

Evolutionary history of endogenous human herpesvirus 6 reflects human migration out of Africa

A Aswad, G Aimola, D Wight… - Molecular Biology …, 2021 - academic.oup.com
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result,∼
70 million people harbor the genome of one of these viruses in every cell of their body. Until …

Chromatin profiles of chromosomally integrated human herpesvirus-6A

AJ Saviola, C Zimmermann, MP Mariani… - Frontiers in …, 2019 - frontiersin.org
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related
betaherpesviruses that are associated with various diseases including seizures and …

Complete genome sequence of germline chromosomally integrated human herpesvirus 6A and analyses integration sites define a new human endogenous virus with …

J Tweedy, MA Spyrou, M Pearson, D Lassner, U Kuhl… - Viruses, 2016 - mdpi.com
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous
genomes, resulting from integration into the germline: chromosomally-integrated “CiHHV …

Increased prevalence of human herpesvirus type 8 (HHV‐8) genome among blood donors from North‐Western Argentina

ML Hulaniuk, O Torres, S Bartoli… - Journal of medical …, 2017 - Wiley Online Library
The prevalence of HHV‐8 infection varies widely in South American populations, displaying
geographical variations in its distribution. The heterogeneous genetic contributions provided …

Update of the global distribution of human gammaherpesvirus 8 genotypes

AO Lopes, N Spitz, CRS Reis, VS de Paula - Scientific Reports, 2021 - nature.com
Abstract Human gammaherpesvirus 8 (HHV-8) consists of six major clades (A–F) based on
the genetic sequence of the open reading frame (ORF)-K1. There are a few conflicting …

Inherited chromosomally integrated human herpesvirus 6 genomes are ancient, intact, and potentially able to reactivate from telomeres

E Zhang, AJ Bell, GS Wilkie, NM Suárez… - Journal of …, 2017 - Am Soc Microbiol
The genomes of human herpesvirus 6A (HHV-6A) and HHV-6B have the capacity to
integrate into telomeres, the essential capping structures of chromosomes that play roles in …

Transmission dynamics of human herpesvirus 6A, 6B and 7 from whole genome sequences of families

BS Chrisman, C He, JY Jung, N Stockham, K Paskov… - Virology Journal, 2022 - Springer
While hundreds of thousands of human whole genome sequences (WGS) have been
collected in the effort to better understand genetic determinants of disease, these whole …