Virus‐like particles as powerful vaccination strategy against human viruses

I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …

Virus-based biological systems as next-generation carriers for the therapy of central nervous system diseases

I Nowak, M Madej, J Secemska, R Sarna… - Pharmaceutics, 2023 - mdpi.com
Central nervous system (CNS) diseases are currently a major challenge in medicine. One
reason is the presence of the blood–brain barrier, which is a significant limitation for …

Nanocarriers of antigen proteins for vaccine delivery

LL Chaves, D Dourado, IB Prunache… - International Journal of …, 2024 - Elsevier
Nanoformulations in vaccinology provide antigen stability and enhanced immunogenicity, in
addition to providing targeted delivery and controlled release. In the last years, much …

A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei

G Yao, H Min, X Yu, F Liu, L Cui, Y Cao - Parasites & Vectors, 2023 - Springer
Background Safe and effective vaccines are crucial for the control and eventual elimination
of malaria. Novel approaches to optimize and improve vaccine efficacy are urgently …

Nucleic Acid Delivery Nanotechnologies for In Vivo Cell Programming

HV Balcorta, VG Contreras Guerrero… - ACS Applied Bio …, 2024 - ACS Publications
In medicine, it is desirable for clinicians to be able to restore function and imbue novel
function into selected cells for therapy and disease prevention. Cells damaged by disease …

B cell immune response to human bocaviruses

C Karaaslan, O Wirz, G Tan, A Globinska… - Clinical & …, 2024 - Wiley Online Library
Abstract Background Human bocaviruses (HBoVs) have been demonstrated in respiratory
and gastrointestinal infections; however, the immune response to them has not been studied …

Overview of the recent advances in porcine epidemic diarrhea vaccines

MZ Wei, L Chen, R Zhang, Z Chen, YJ Shen… - The Veterinary …, 2024 - Elsevier
Vaccination is the most effective means of preventing and controlling porcine epidemic
diarrhea (PED). Conventional vaccines developed from porcine epidemic diarrhea virus …

[HTML][HTML] Plant-Produced Chimeric Hepatitis E Virus-like Particles as Carriers for Antigen Presentation

ES Mardanova, EA Vasyagin, KG Kotova… - Viruses, 2024 - mdpi.com
A wide range of virus-like particles (VLPs) is extensively employed as carriers to display
various antigens for vaccine development to fight against different infections. The plant …

Current Progress in the Science of Novel Adjuvant Nano-Vaccine-Induced Protective Immune Responses

MA Saleemi, Y Zhang, G Zhang - Pathogens, 2024 - mdpi.com
Vaccinations are vital as they protect us from various illness-causing agents. Despite all the
advancements in vaccine-related research, developing improved and safer vaccines against …

[HTML][HTML] Computational method for designing vaccines applied to virus-like particles (VLPs) as epitope carriers

P Prosper, RR Puertas, DMA Guérin, MM Branda - Vaccine, 2024 - Elsevier
Nonenveloped virus-like particles (VLPs) are self-assembled oligomeric structures
composed of one or more proteins that originate from diverse viruses. Because these VLPs …