Background The aim of the present paper is to construct an emulator of a complex biological
system simulator using a machine learning approach. More specifically, the simulator is a …

Dengue and zika are amongst the most prevalent mosquito-borne diseases caused by
closely related members Dengue virus (DENV) and Zika virus (ZIKV), respectively, of the …

The really interesting thing about herpesviruses is that they can establish lifelong persistant
infections in immunocompetent hosts. At first glance, they would seem to have very different …

Immunological studies frequently analyze individual components (eg, signaling pathways) of
immune systems in a reductionist manner. In contrast, systems immunology aims to give a …

Background The aim of a recent research project was the investigation of the mechanisms
involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the …

The building blocks of these systems consist of a collection of variables (mapping to agents),
a graph that captures the dependence relations of agents on other agents, a local update …

Monkeypox virus is a member of the Poxviridae family, which causes monkeypox zoonotic
disease. Since July 2022, the prevention of monkeypox have become more considerable …

Motivation: An unbalanced differentiation of T helper cells from precursor type TH0 to the
TH1 or TH2 phenotype in immune responses often leads to a pathological condition. In …

Background. Type 2 diabetes (T2D) is a chronic metabolic disease potentially leading to
serious widespread tissue damage. Human organism develops T2D when the glucose …

Motivation A computational model equipped with the main immunological features of the sea
bass (Dicentrarchus labrax L.) immune system was used to predict more effective …