Epstein-Barr virus (HHV-4) inoculation to rabbits by intranasal and oral routes results in subacute and/or persistent infection dissimilar to human disease

J Rajčáni, K Szenthe, V Ďurmanová, A Tóth, B Ásványi… - Intervirology, 2014 - karger.com
Objective: We report the infection of New Zealand white rabbits with Epstein-Barr virus
(EBV). Methods: EBV prepared in B95-8 (producer) cells was inoculated to rabbits by …

Immune control of HIV-1 infection after therapy interruption: immediate versus deferred antiretroviral therapy

P Paci, R Carello, M Bernaschi, G D'Offizi… - BMC Infectious …, 2009 - Springer
Background The optimal stage for initiating antiretroviral therapies in HIV-1 bearing patients
is still a matter of debate. Methods We present computer simulations of HIV-1 infection …

Alternating host cell tropism shapes the persistence, evolution and coexistence of epstein–barr virus infections in human

GT Huynh, FR Adler - Bulletin of mathematical biology, 2011 - Springer
Epstein–Barr virus (EBV) infects and can persist in a majority of people worldwide. Within an
infected host, EBV targets two major cell types, B cells and epithelial cells, and viruses …

[HTML][HTML] Immunoinformatics approach in designing a novel vaccine using epitopes from all the structural proteins of SARS-CoV-2

LRM Herrera - Biomedical and Pharmacology Journal, 2020 - biomedpharmajournal.org
The rapid transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has resulted to the death of hundreds of thousands of people worldwide. With the …

Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm

AL Woelke, J von Eichborn, MS Murgueitio, CL Worth… - PloS one, 2011 - journals.plos.org
Peptide vaccination in cancer therapy is a promising alternative to conventional methods.
However, the parameters for this personalized treatment are difficult to access …

Rational design of B-cell and T-cell multi epitope-based vaccine against Zika virus, an in silico study

M Ganji, S Bakhshi, K Ahmadi, A Shoari… - Journal of …, 2024 - Taylor & Francis
The Zika virus (ZKV) is a single-stranded positive-sense, enveloped RNA virus. Zika
infection during pregnancy can cause congenital microcephaly, Guillain-Barré syndrome …

[PDF][PDF] Agent-based simulation of the immune system

N Fachada - Master's thesis, Instituto Superior Técnico, Lisboa …, 2008 - researchgate.net
Computational models of the immune system have several applications, such as theory
testing and validation, or as a complement to first stages of drug testing. The majority of …

Multi-scale simulation of T helper lymphocyte differentiation

P Tieri, V Prana, T Colombo, D Santoni… - … in Bioinformatics and …, 2014 - Springer
The complex differentiation process of the CD4+ T helper lymphocytes shapes the form and
the range of the immune response to different antigenic challenges. Few mathematical and …

[PDF][PDF] Métodos matemáticos para modelos basados en agentes

BA Buffa - Universidad Nacional de Córdoba, Córdoba, Argentina, 2015 - core.ac.uk
En este trabajo se desarrolla un marco matemático para el abordaje de los Modelos
Basados en Agentes. Dicho marco es el denominado marco de los modelos algebraicos, el …

Computer modeling of clonal dominance: memory-anti-naive and its curbing by attrition

F Castiglione, D Ghersi, F Celada - Frontiers in immunology, 2019 - frontiersin.org
Experimental and computational studies have revealed that T-cell cross-reactivity is a
widespread phenomenon that can either be advantageous or detrimental to the host. In …