Computational models as novel tools for cancer vaccines

F Castiglione, PL Lollini, S Motta, A Paladini… - New Challenges for …, 2012 - Springer
Prevention of tumor growth by immunological approaches is based on the assumption that
the immune system, if adequately stimulated before tumor onset, could be able to protect …

Modeling and Simulating Influenza with Immune-B

S Zou, X Yang, Z Du, Y Jin - 2013 10th Web Information System …, 2013 - ieeexplore.ieee.org
Influenza virus causes an acute, mostly self-limited, infection of the upper respiratory tract.
Several aspects of influenza infections are still unresolved. Most of these unresolved …

Algebraic theory for discrete models in systems biology

F Hinkelmann - 2011 - vtechworks.lib.vt.edu
This dissertation develops algebraic theory for discrete models in systems biology. Many
discrete model types can be translated into the framework of polynomial dynamical systems …

Epitope screening and cell cooperation in the immune response

F Castiglione, M Bernaschi - 2011 Second International …, 2011 - ieeexplore.ieee.org
We present a combination of techniques of systems biology and immunoinformatics to
simulate the immune response. Amino acid sequences representing molecular binding sites …

Immunoinformatics: an overview of computational tools and techniques for understanding immune function

M Von Herrath, P Taylor - Expert Review of Clinical Immunology, 2007 - Taylor & Francis
In recent years, there has been a rapid expansion in the application of information
technology to biological data. Although the use of information science techniques is less …

Aplicación de vida artificial al estudio de vacunas para el control del virus de papiloma humano tipo 16

ME Escobar Ospina - 2016 - repositorio.unal.edu.co
Este trabajo de investigación presenta un modelo de vida artificial inspirado en el ciclo de
vida del virus de papiloma humano tipo 16 (como agente etiológico de cáncer cervical), en …

[PDF][PDF] Plasma Cell Negative Regulation Mechanism Based Artificial Immune System

X Dong, Y Guan, J Yang - Proceedings of the 2013 Fourth …, 2013 - researchgate.net
Plasma cell negative regulation mechanism is taken to construct an artificial immune system
by complex system modeling, which is to complete immune theories of existing artificial …

Hybrid Parallel Computing Strategies for Scientific Computing Applications

JH Lee - 2012 - vtechworks.lib.vt.edu
Abstract Multi-core, multi-processor, and Graphics Processing Unit (GPU) computer
architectures pose significant challenges with respect to the efficient exploitation of …

[PDF][PDF] Research Article How the Interval between Prime and Boost Injection Affects the Immune Response in a Computational Model of the Immune System

F Castiglione, F Mantile, P De Berardinis, A Prisco - 2012 - academia.edu
The immune system is able to respond more vigorously to the second contact with a given
antigen than to the first contact. Vaccination protocols generally include at least two doses …

[PDF][PDF] Biophysical Modeling using Cellular Automata

B Pfeifer - Cellular Automata-Simplicity Behind Complexity, 2011 - Citeseer
The definition of a model is as following: a model is an abstract and simplified picture of a
reality in the world. From this definition it can be derived that each biomedical model is an …