DNA damage-inducing anticancer therapies: from global to precision damage

TGA Reuvers, R Kanaar, J Nonnekens - Cancers, 2020 - mdpi.com
DNA damage-inducing therapies are of tremendous value for cancer treatment and function
by the direct or indirect formation of DNA lesions and subsequent inhibition of cellular …

Artificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care

E Trivizakis, GZ Papadakis… - International …, 2020 - spandidos-publications.com
The new era of artificial intelligence (AI) has introduced revolutionary data‑driven analysis
paradigms that have led to significant advancements in information processing techniques …

An overview of nanoscale radionuclides and radiolabeled nanomaterials commonly used for nuclear molecular imaging and therapeutic functions

L Farzin, S Sheibani, ME Moassesi… - Journal of Biomedical …, 2019 - Wiley Online Library
Recent advances in the field of nanotechnology applications in nuclear medicine offer the
promise of better diagnostic and therapeutic options. In recent years, increasing efforts have …

Gold nanoparticles and nanorods in nuclear medicine: A mini review

D Maccora, V Dini, C Battocchio, I Fratoddi, A Cartoni… - Applied Sciences, 2019 - mdpi.com
In the last decade, many innovative nanodrugs have been developed, as well as many
nanoradiocompounds that show amazing features in nuclear imaging and/or radiometabolic …

Review of extremity dosimetry in nuclear medicine

R Kollaard, A Zorz, J Dabin, P Covens… - Journal of …, 2021 - iopscience.iop.org
The exposure of the fingers is one of the major radiation protection concerns in nuclear
medicine (NM). The purpose of this paper is to provide an overview of the exposure …

Current strategies of radiopharmaceuticals in theranostic applications

P Shende, S Gandhi - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
Conventional chemotherapy treatment for cancer tends to show severe systemic toxicities
like hair loss (alopecia), anemia, diarrhea, edema and loss of appetite …

Glucose-functionalized liposomes for reducing false positives in cancer diagnosis

C Tzror-Azankot, O Betzer, T Sadan, M Motiei… - ACS …, 2020 - ACS Publications
Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a powerful tool for
cancer detection, staging, and follow-up. However, 18F-FDG-PET imaging has high rates of …

[HTML][HTML] Production of nuclear medicine radioisotopes with ultra-intense lasers

Z Sun - AIP Advances, 2021 - pubs.aip.org
In the last two decades, there has been a strong research interest in producing
radioisotopes with ultra-intense lasers, as an application of laser-driven accelerators in …

LC–MS/MS Bioanalysis of Radioligand Therapeutic Drug Candidate for Preclinical Toxicokinetic Assessment

Y Fu, J Farnham, W Li, B Powers… - Analytical …, 2023 - ACS Publications
Radioligand therapy (RLT) has gained significant momentum in recent years in the
diagnosis, treatment, and monitoring of cancers. In preclinical development, the safety …

Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy

P Guzik, M Benešová, M Ratz… - European journal of …, 2021 - Springer
Purpose The folate receptor (FR) is frequently overexpressed in a variety of tumor types and,
hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a …