Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …

Introduction Natural killer (NK) cells are key anti-tumor effectors of the innate immunity.
Phenotypic differences allow us to discriminate in between three functional stages of …

The field of immunogenomics has the opportunity for accelerated genetic discovery aided by
the maturation of electronic health records (EHRs) linked to DNA biobanks. Novel analysis …

Endemic Burkitt lymphoma (eBL) is a fast-growing germinal center B cell lymphoma,
affecting 5–10 per 100,000 children annually, in the equatorial belt of Africa. We hypothesize …

Simple Summary Natural killer (NK) cells are key cytotoxic effectors against leukemic cells.
The polymorphism of killer cell immunoglobulin-like receptor (KIR) genes plays a crucial role …

HLA-B* 57: 01 is an HLA allelic variant associated with positive outcomes during viral
infections through interactions with T cells and NK cells, but severe disease in persons …

The innate immune system is important in clearing infections and maintaining homeostasis.
Across vertebrates, innate immunity is capable of executing potent effector responses …

Human immunodeficiency virus (HIV) is a formidable infection targeting the intricate defense
mechanisms of the human body, primarily focusing its assault on the vital white blood cells …