[PDF][PDF] Neuroanatomical assessment of biological maturity
Structural MRI allows unparalleled in vivo study of the anatomy of the developing human
brain. For more than two decades [1], MRI research has revealed many new aspects of this …
brain. For more than two decades [1], MRI research has revealed many new aspects of this …
DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples
SE Jung, SM Lim, SR Hong, EH Lee, KJ Shin… - Forensic Science …, 2019 - Elsevier
Many studies have reported age-associated DNA methylation changes and age-predictive
models in various tissues and body fluids. Although age-associated DNA methylation …
models in various tissues and body fluids. Although age-associated DNA methylation …
[HTML][HTML] Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
Age of Huntington's disease (HD) motoric onset is strongly related to the number of CAG
trinucleotide repeats in the huntingtin gene, suggesting that biological tissue age plays an …
trinucleotide repeats in the huntingtin gene, suggesting that biological tissue age plays an …
Improved age determination of blood and teeth samples using a selected set of DNA methylation markers
Age estimation from DNA methylation markers has seen an exponential growth of interest,
not in the least from forensic scientists. The current published assays, however, can still be …
not in the least from forensic scientists. The current published assays, however, can still be …
[HTML][HTML] Stress, diet, exercise: common environmental factors and their impact on epigenetic age
F Galkin, O Kovalchuk, D Koldasbayeva… - Ageing Research …, 2023 - Elsevier
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …
health conditions in clinical and research settings. They have enabled geroscientists to …
Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation
X-chromosome inactivation (XCI) achieves dosage compensation between males and
females through the silencing of the majority of genes on one of the female X chromosomes …
females through the silencing of the majority of genes on one of the female X chromosomes …
Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
It is now well established that the genomic landscape of DNA methylation (DNAm) gets
altered as a function of age, a process we here call 'epigenetic drift'. The biological …
altered as a function of age, a process we here call 'epigenetic drift'. The biological …
Kinetics and mechanisms of mitotic inheritance of DNA methylation and their roles in aging-associated methylome deterioration
Mitotic inheritance of the DNA methylome is a challenging task for the maintenance of cell
identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully …
identity. Whether DNA methylation pattern in different genomic contexts can all be faithfully …
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging
Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …
on patterns of DNA methylation—can be computed and is associated with an array of factors …
Methylation-based biological age and breast cancer risk
Background Age is one of the strongest predictors of cancer, chronic disease, and mortality,
but biological responses to aging differ among people. Epigenetic DNA modifications have …
but biological responses to aging differ among people. Epigenetic DNA modifications have …