Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia

MH Kwack, OB Hamida, MK Kim, MK Kim, YK Sung - Scientific Reports, 2023 - nature.com
Androgenetic alopecia (AGA), also known as male pattern baldness, is a common hair loss
condition influenced by genetic and hormonal factors. Variations in gene expression and …

The role of endoglin in post-ischemic revascularization

E Núñez-Gómez, M Pericacho, C Ollauri-Ibáñez… - Angiogenesis, 2017 - Springer
Following arterial occlusion, blood vessels respond by forming a new network of functional
capillaries (angiogenesis), by reorganizing preexisting capillaries through the recruitment of …

Reduced expression of transforming growth factor β1 exacerbates pathology in an experimental asthma model

W Scherf, S Burdach, G Hansen - European journal of …, 2005 - Wiley Online Library
Allergic asthma is characterized by airway hyperreactivity (AHR), eosinophilic airway
inflammation and elevated serum IgE levels. T‐helper 2 (Th2) cells play a critical role in the …

Endoglin in the spotlight to treat cancer

T González Muñoz, AT Amaral… - International Journal of …, 2021 - mdpi.com
A spotlight has been shone on endoglin in recent years due to that fact of its potential to
serve as both a reliable disease biomarker and a therapeutic target. Indeed, endoglin has …

Endoglin in human liver disease and murine models of liver fibrosis—A protective factor against liver fibrosis

M Alsamman, V Sterzer, SK Meurer, H Sahin… - Liver …, 2018 - Wiley Online Library
Abstract Background & Aims Liver fibrosis is the outcome of chronic liver injury.
Transforming growth factor‐β (TGF‐β) is a major profibrogenic cytokine modulating hepatic …

Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome

LA Henry, DA Johnson, D Sarrió, S Lee, PR Quinlan… - Oncogene, 2011 - nature.com
Tumor growth factor-β (TGF-β) signaling in cancer has been implicated in growth
suppression of early lesions and enhancing tumor cell invasion and metastasis. However …

Reduced tumor growth and angiogenesis in endoglin-haploinsufficient mice

A Düwel, N Eleno, M Jerkic, M Arevalo, JP Bolaños… - Tumor biology, 2006 - karger.com
Endoglin is a transforming growth factor-β1 (TGF-β1) accessory receptor which is highly
expressed in tumor vessels. To study the role of endoglin in tumor growth and angiogenesis …

Microvascular density of regenerative nodule to small hepatocellular carcinoma by automated analysis using CD105 and CD34 immunoexpression

JP Paschoal, V Bernardo, NHS Canedo, OD Ribeiro… - BMC cancer, 2014 - Springer
Background Angiogenesis is a proliferative process resulting in the development of new
blood vessels from existing endothelial cells and is considered crucial for tumor growth and …

A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle

MI Calvo-Sánchez, S Fernández-Martos… - Journal of Molecular …, 2019 - academic.oup.com
The hair follicle is a biological oscillator that alternates growth, regression, and rest phases
driven by the sequential activation of the proliferation/differentiation programs of resident …

Interplay between Podoplanin, CD44s and CD44v in squamous carcinoma cells

L Montero-Montero, J Renart, A Ramírez, C Ramos… - Cells, 2020 - mdpi.com
Podoplanin and CD44 are transmembrane glycoproteins involved in inflammation and
cancer. In this paper, we report that podoplanin is coordinately expressed with the CD44 …