Outlook and opportunities for engineered environments of breast cancer dormancy

NR Richbourg, N Irakoze, H Kim, SR Peyton - Science Advances, 2024 - science.org
Dormant, disseminated breast cancer cells resist treatment and may relapse into malignant
metastases after decades of quiescence. Identifying how and why these dormant breast …

Mesenchymal Stem Cell-Secreted Exosomes and Soluble Signals Regulate Breast Cancer Metastatic Dormancy: Current Progress and Future Outlook

B Dai, AM Clark, A Wells - International Journal of Molecular Sciences, 2024 - mdpi.com
Breast cancer is most common in women, and in most cases there is no evidence of spread
and the primary tumor is removed, resulting in a 'cure'. However, in 10% to 30% of these …

Collagen Mineralization Decreases NK Cell‐Mediated Cytotoxicity of Breast Cancer Cells via Increased Glycocalyx Thickness

S Park, S Choi, AA Shimpi, LA Estroff… - Advanced …, 2024 - Wiley Online Library
Skeletal metastasis is common in patients with advanced breast cancer and often caused by
immune evasion of disseminated tumor cells (DTCs). In the skeleton, tumor cells not only …

State of the Art Modelling of the Breast Cancer Metastatic Microenvironment: Where Are We?

M Nuckhir, D Withey, S Cabral, H Harrison… - Journal of Mammary …, 2024 - Springer
Metastatic spread of tumour cells to tissues and organs around the body is the most frequent
cause of death from breast cancer. This has been modelled mainly using mouse models …

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

A Lamouline, S Bersini, M Moretti - Frontiers in Oncology, 2023 - frontiersin.org
Even though breast cancers usually have a good outcome compared to other tumors, the
cancer can progress and create metastases in different parts of the organism, the bone …

具有休眠特征的播散肿瘤细胞体内外研究模型的建立及应用

阙祖俊, 刘佳君, 田建辉 - 肿瘤防治研究, 2023 - zlfzyj.com
摘要术后无症状的早期癌症(肺癌) 患者的转移靶器官中已经潜伏有处于休眠状态的播散肿瘤
细胞(DTCs), 其增殖是导致临床转移发生的关键环节. 开发维持DTCs 休眠或根除休眠DTCs …

In vitro models of breast cancer bone metastasis

A Lamouline, S Bersini, M Moretti - Frontiers in oncology, 2023 - folia.unifr.ch
According to the World Health Organization, breast cancer is the most common cancer
worldwide as of 2020, with the number of diagnoses having nearly doubled in the last two …

Utilizing a Dynamic Well-defined 3D Co-culture Model for Investigations in ER+ Breast Cancer Dormancy

DVL Moore - 2024 - udspace.udel.edu
Prevention of late breast cancer recurrences remains a clinical challenge for physicians.
Detection of dormant cancer cells, which are often few in number, is challenging within …

[图书][B] The Effect of the Placental Microenvironment on Drug Delivery for Treatment of Preeclampsia

KM Nelson - 2023 - search.proquest.com
Abstract Preeclampsia (PE) occurs in 5-8% of pregnant people and accounts for about 12%
of pregnancy-related mortality worldwide. PE is characterized by maternal hypertension …

Establishment and Application of in vitro and in vivo Model of Disseminated Tumor Cells with Dormancy

QUE Zujun, T Jianhui - Cancer Research on Prevention and Treatment, 2023 - zlfzyj.com
Postoperative asymptomatic patients with early cancer (lung cancer) have dormant
disseminated tumor cells (DTCs) in their metastatic target organs, and the proliferation of …