Unraveling the tumor microenvironment: insights into cancer metastasis and therapeutic strategies

M El-Tanani, SA Rabbani, R Babiker, I Rangraze… - Cancer Letters, 2024 - Elsevier
This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

Cholinergic Mechanisms in Gastrointestinal Neoplasia

N Sampaio Moura, A Schledwitz, M Alizadeh… - International Journal of …, 2024 - mdpi.com
Acetylcholine-activated receptors are divided broadly into two major structurally distinct
classes: ligand-gated ion channel nicotinic and G-protein-coupled muscarinic receptors …

Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients

P Nikeghbal, D Burke, MP Steinkamp - bioRxiv, 2024 - biorxiv.org
Ovarian cancer (OC) remains the deadliest gynecological cancer, primarily due to late stage
diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative …