Maintaining the balance of a cell's redox function is key to determining cell fate. In the critical
redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent …

Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Abstract microRNAs (also known as miRNAs or miRs) are a class of small non-coding RNAs
that play a critical role in post-transcriptional gene regulation as negative gene regulators by …

Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …

Integrins are transmembrane receptors that possess distinct ligand-binding specificities in
the extracellular domain and signaling properties in the cytoplasmic domain. While most …

Oxidative stress is one of the hallmarks of cancer. Tumorigenesis and progression are
accompanied by elevated reactive oxygen species (ROS) levels and adaptive elevation of …

WNT/β-catenin signaling is a highly complex pathway that plays diverse roles in various
cellular processes. While WNT ligands usually signal through their dedicated Frizzled …

Monoclonal antibodies (mAbs) as biological macromolecules have been remarked the large
and growing pipline of the pharmaceutical market and also the most promising tool in …