Syndromic obesity with neurodevelopmental delay: opportunities for targeted interventions

TA Kehinde, A Bhatia, B Olarewaju, MZ Shoaib… - European Journal of …, 2022 - Elsevier
Obesity is a growing public health problem in many developed countries, although similar
trends are increasingly being described in some developing nations. The genetic …

Prader–Willi syndrome in adults: an update on nutritional treatment and pharmacological approach

L Barrea, C Vetrani, D Fintini, G De Alteriis… - Current Obesity …, 2022 - Springer
Abstract Purpose of Review Prader–Willi syndrome (PWS) is a rare and complex genetic
disorder with multiple effects on the metabolic, endocrine, and neurological systems, as well …

Caring and living with Prader-Willi syndrome in Italy: integrating children, adults and parents' experiences through a multicentre narrative medicine research

L Ragusa, A Crinò, G Grugni, L Reale, A Fiorencis… - BMJ open, 2020 - bmjopen.bmj.com
Objectives Prader-Willi syndrome (PWS) significantly impacts health-related quality of life;
however, its relational and existential aspects remain unknown in Italian clinical and social …

Prader–Willi syndrome: Symptoms and topiramate response in light of genetics

C Louveau, MC Turtulici, A Consoli, C Poitou… - Frontiers in …, 2023 - frontiersin.org
Introduction Prader–Willi Syndrome (PWS) is a rare genetic condition, which affects one in
25,000 births and results in various phenotypes. It leads to a wide range of metabolic and …

A pro-inflammatory phenotype is associated with behavioural traits in children with Prader–Willi syndrome

M Krefft, D Frydecka, G Zalsman… - European child & …, 2021 - Springer
Several lines of evidence indicate that immune-inflammatory alterations are widely observed
in various mental disorders. Genetic syndromes with high risk of psychiatric disorders may …

Altered gesture imitation and brain anatomy in adult Prader–Willi Syndrome Patients

A Caixàs, L Blanco-Hinojo, J Pujol, J Deus… - Journal of the …, 2021 - cambridge.org
Objective: To explore motor praxis in adults with Prader–Willi syndrome (PWS) in
comparison with a control group of people with intellectual disability (ID) and to examine the …

An Exploratory Analysis on the 2D: 4D Digit Ratio and Its Relationship with Social Responsiveness in Adults with Prader–Willi Syndrome

S Gámez, J Cobo, M Fernández-Lafitte… - Journal of Clinical …, 2023 - mdpi.com
Prader–Willi syndrome (PWS) is a genetic disorder produced by a lack of expression of
paternally derived genes in the 15q11–13 region. Research has generally focused on its …

One year of recombinant human growth hormone treatment in adults with Prader–Willi syndrome improves body composition, motor skills and brain functional activity …

L Casamitjana, L Blanco-Hinojo… - Journal of clinical …, 2022 - mdpi.com
We compared body composition, biochemical parameters, motor function, and brain neural
activation in 27 adults with Prader–Willi syndrome and growth-hormone deficiency versus …

Social responsiveness and psychosocial functioning in adults with Prader–Willi syndrome

M Fernández-Lafitte, J Cobo, R Coronas… - Journal of clinical …, 2022 - mdpi.com
Although various studies have investigated symptoms of autism spectrum disorder (ASD) in
Prader–Willi syndrome (PWS), little is known about the consequences of these symptoms …

Hyperorality in frontotemporal dementia: Cognitive and psychiatric symptom profiles in early-stage disease

CB Morrow, GAS Chaney, D Capuzzi… - Journal of …, 2022 - content.iospress.com
Hyperorality is a distinctive feature of the behavioral variant of frontotemporal dementia
(bvFTD), but little is known about its significance in early-stage disease. This study …