The use of probiotics, prebiotics, synbiotics or fermented foods can modulate the gut-brain
axis and constitute a potentially therapeutic intervention in psychiatric disorders. This …

Purpose This study aims to evaluate and summarize the effectiveness of cognitive
behavioral therapy (CBT) and internet-based CBT (ICBT) interventions on relapse …

In both the ICD-11 and the DSM-5, the core symptoms of depression are reported to be
depressed mood (eg, feeling sad, down or hopeless) and markedly diminished interest or …

Background & aims We aimed to analyze the prospective association between adherence to
the ultra-processed dietary pattern and risk of depressive outcomes using original data from …

Depression, a global health problem with growing prevalence, brings serious impacts on the
daily life of patients. However, the antidepressants currently used in clinical are not perfectly …

Introduction and aims Treatment-resistant depression (TRD) occurs when at least two
different antidepressants, taken at the right dosage, for adequate period of time and with …

Background Major depressive disorder (MDD) is a common and debilitating mental illness
characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily …

Major depressive disorder (MDD) is a heterogeneous syndrome, associated with different
levels of severity and impairment on the personal functioning for each patient. Classification …

Background: Depression is a severe mental disorder that poses a significant threat to both
the physical and mental wellbeing of individuals. Currently, there are various methods for …

Background Anhedonia, a core diagnostic feature for major depressive disorder (MDD), is
defined as the loss of pleasure and interest in daily activities. Its prevalence in MDD patients …