Long-term complications of COVID-19

AD Desai, M Lavelle… - American Journal of …, 2022 - journals.physiology.org
SARS-CoV-2 has rapidly spread across the globe and infected hundreds of millions of
people worldwide. As our experience with this virus continues to grow, our understanding of …

[HTML][HTML] Long COVID or post-acute sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms

AD Proal, MB VanElzakker - Frontiers in microbiology, 2021 - frontiersin.org
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …

Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study

R Gloeckl, D Leitl, I Jarosch, T Schneeberger… - ERJ open …, 2021 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19) can result in a large variety of chronic
health issues such as impaired lung function, reduced exercise performance and diminished …

Lung fibrosis after COVID-19: treatment prospects

E Bazdyrev, P Rusina, M Panova, F Novikov… - Pharmaceuticals, 2021 - mdpi.com
At the end of 2019, a highly contagious infection began its ominous conquest of the world. It
was soon discovered that the disease was caused by a novel coronavirus designated as …

Chest CT of lung injury 1 year after COVID-19 pneumonia: the CovILD study

AK Luger, T Sonnweber, L Gruber, C Schwabl, K Cima… - Radiology, 2022 - pubs.rsna.org
Background The long-term pulmonary sequelae of COVID-19 is not well known. Purpose To
characterize patterns and rates of improvement of chest CT abnormalities 1 year after …

[HTML][HTML] From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?

JE Michalski, JS Kurche, DA Schwartz - Translational Research, 2022 - Elsevier
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and
scientific communites since it was first reported in late 2019, we are only beginning to …

Post COVID-19 sequelae: A prospective observational study from Northern India

S Naik, SN Haldar, M Soneja… - Drug discoveries & …, 2021 - jstage.jst.go.jp
Post COVID-19 sequelae are a constellation of symptoms often reported after recovering
from COVID-19. There is a need to better understand the clinical spectrum and long-term …

COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) followed by repair with lung remodeling is
observed in COVID-19. These findings can lead to pulmonary terminal fibrosis, a form of …

Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis

A Singh, S Chakraborty, SW Wong… - Proceedings of the …, 2022 - National Acad Sciences
The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune
pathways that release inflammatory cytokines and growth factors such as tumor growth …

Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals

HM Al-Kuraishy, GES Batiha, H Faidah… - …, 2022 - Springer
Pirfenidone (PFN) is an anti-fibrotic drug with significant anti-inflammatory property used for
treatment of fibrotic conditions such as idiopathic pulmonary fibrosis (IPF). In the coronavirus …