BACKGROUND Intraamniotic inflammation is associated with preterm birth, especially in
cases occurring before 32 weeks' gestation, and is causally linked with an increased risk for …

Perinatal sepsis and inflammation trigger lung and brain injury in preterm infants, and
associated apnea of prematurity. We hypothesized that endotoxin exposure in the immature …

Chorioamnionitis is associated with preterm labor and fetal inflammatory response
syndrome (FIRS), causing fetal organ injury and morbidity, particularly in extremely …

Background Intrauterine infection/inflammation plays an important role in the development of
lung injury and bronchopulmonary dysplasia (BPD) in preterm infants, While a multifactorial …

In recent years, translational research with various animal models has been helpful to
answer basic questions about the effect of antenatal inflammation on maturation and …

Preterm birth is defined as delivery at< 37 weeks of gestational age (GA) and exposes 15
million infants worldwide to serious early life diseases. Lowering the age of viability to 22 …

Background The human fetus is able to mount a systemic inflammatory response when
exposed to microorganisms. This stereotypic response has been termed the 'fetal …

Chorioamnionitis and fetal sepsis can induce a fetal inflammatory response syndrome
(FIRS) which is closely related to the development of white matter injury in the fetal brain …

Background Chorioamnionitis and fetal inflammation are principal causes of neuropathology
detected after birth, particularly in very preterm infants. Preclinical studies show that …

Background Epidural-related maternal fever (ERMF) has been reported in∼ 26% of
labouring women. The underlying mechanisms remain unclear. We hypothesised that ERMF …