Diameter refinement of electrospun nanofibers: From mechanism, strategies to applications

X Wen, J Xiong, S Lei, L Wang, X Qin - Advanced Fiber Materials, 2021 - Springer
Electrospinning has drawn wide attention for its powerful capacity to produce ultrafine
nanofibers (UNFs) from various materials. These UNFs demonstrated significantly enhanced …

The importance of 3D fibre architecture in cancer and implications for biomaterial model design

JC Ashworth, TR Cox - Nature Reviews Cancer, 2024 - nature.com
The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Matrix mechanophysical factor: pore size governs the cell behavior in cancer

M Saif Ur Rahman, J Wu, H Chen, C Sun… - … in Physics: X, 2023 - Taylor & Francis
Cancer tissues are a heterogeneously multifaceted assembly. Understanding the
relationship of tumors with their microenvironment is also required to understand the tumor …

Artificial tumor matrices and bioengineered tools for tumoroid generation

YC Liu, P Chen, R Chang, X Liu, JW Jhang… - …, 2024 - iopscience.iop.org
The tumor microenvironment (TME) is critical for tumor growth and metastasis. The TME
contains cancer-associated cells, tumor matrix, and tumor secretory factors. The fabrication …

Breast cancer cell cultures on electrospun poly (ε-caprolactone) as a potential tool for preclinical studies on anticancer treatments

B Bazzolo, E Sieni, A Zamuner, M Roso, T Russo… - Bioengineering, 2020 - mdpi.com
During anticancer drug development, most compounds selected by in vitro screening are
ineffective in in vivo studies and clinical trials due to the unreliability of two-dimensional (2D) …

Biocompatibility of electrospun cell culture scaffolds made from balangu seed mucilage/PVA composites

A Allafchian, S Saeedi, SAH Jalali - Nanotechnology, 2021 - iopscience.iop.org
Abstract Synthesis of Balangu (Lallemantia royleana) seed mucilage (BSM) solutions
combined with polyvinyl alcohol (PVA) was studied for the purpose of producing 3D …

Recent advances in scaffold based electrospun for breast cancer research

P Ebrahimbaygi, MR Khazaei… - Polymers for …, 2024 - Wiley Online Library
One of the biggest challenges facing public health in the modern era is the management of
cancer, a global health issue. Breast cancer (BC) is the most common malignancy among …

Electrospun drug-loaded and gene-loaded nanofibres: the holy grail of glioblastoma therapy?

L Louis, BS Chee, M McAfee, M Nugent - Pharmaceutics, 2023 - mdpi.com
To date, GBM remains highly resistant to therapies that have shown promising effects in
other cancers. Therefore, the goal is to take down the shield that these tumours are using to …

Cancer Stem Cells Niche Regulation Within the Tumor Microenvironment

Z Siddiqui, Z Equbal, N Muhammad, D Usmani… - Current Tissue …, 2024 - Springer
Abstract Purpose of Review Several cancer stem cells (CSCs) niches have been identified
in the tumor microenvironment. Hence, it is important to review the underlying mechanisms …

Advanced scaffold design via electrospinning

Y Zhao, J Xiong - 2022 - books.rsc.org
The term nanofibers refers to fibers with a diameter ranging from 1 to 1000 nanometers. 1, 2
Based on their composition, nanofibers can be divided into organic fibers, inorganic fibers …