[HTML][HTML] Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

BrainAGE, brain health, and mental disorders: A systematic review

J Seitz-Holland, SS Haas, N Penzel… - Neuroscience & …, 2024 - Elsevier
The imaging-based method of brainAGE aims to characterize an individual's vulnerability to
age-related brain changes. The present study systematically reviewed brainAGE findings in …

Fractional dynamics foster deep learning of COPD stage prediction

C Yin, M Udrescu, G Gupta, M Cheng, A Lihu… - Advanced …, 2023 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death
worldwide. Current COPD diagnosis (ie, spirometry) could be unreliable because the test …

[HTML][HTML] Toward MR protocol-agnostic, unbiased brain age predicted from clinical-grade MRIs

PA Valdes-Hernandez, C Laffitte Nodarse… - Scientific Reports, 2023 - nature.com
The difference between the estimated brain age and the chronological age ('brain-PAD')
could become a clinical biomarker. However, most brain age models were developed for …

eXplainable Artificial Intelligence (XAI) in aging clock models

A Kalyakulina, I Yusipov, A Moskalev… - Ageing Research …, 2023 - Elsevier
XAI is a rapidly progressing field of machine learning, aiming to unravel the predictions of
complex models. XAI is especially required in sensitive applications, eg in health care, when …

Explainable brain age prediction using covariance neural networks

S Sihag, G Mateos, C McMillan… - Advances in Neural …, 2024 - proceedings.neurips.cc
In computational neuroscience, there has been an increased interest in developing machine
learning algorithms that leverage brain imaging data to provide estimates of" brain age" for …

[HTML][HTML] Feasibility of brain age predictions from clinical T1-weighted MRIs

PA Valdes-Hernandez, CL Nodarse, JH Cole… - Brain Research …, 2023 - Elsevier
An individual's brain predicted age minus chronological age (brain-PAD) obtained from
MRIs could become a biomarker of disease in research studies. However, brain age reports …

Significant acceleration of regional brain aging and atrophy after mild traumatic brain injury

AF Shida, RJ Massett, P Imms… - The Journals of …, 2023 - academic.oup.com
Brain regions' rates of age-related volumetric change after traumatic brain injury (TBI) are
unknown. Here, we quantify these rates cross-sectionally in 113 persons with recent mild …

[HTML][HTML] Modulating effects of zingiberaceae phenolic compounds on neurotrophic factors and their potential as neuroprotectants in brain disorders and age …

AM Razak, JK Tan, M Mohd Said, S Makpol - Nutrients, 2023 - mdpi.com
The Zingiberaceae family possess various phenolic compounds that have significant
systemic bioactivities in the brain, including in age-related neurodegenerative diseases …

Towards a foundation model for brain age prediction using covariance neural networks

S Sihag, G Mateos, A Ribeiro - arXiv preprint arXiv:2402.07684, 2024 - arxiv.org
Brain age is the estimate of biological age derived from neuroimaging datasets using
machine learning algorithms. Increasing brain age with respect to chronological age can …