Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that mainly affects
synovial joints. During the course of RA, the synovium transforms into hyperplastic invasive …

Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor
development and normal development of the lung, kidney, and lymphatic vascular systems …

Emergent physical properties of tissues are not readily understood by reductionist studies of
their constituent cells. Here, we show molecular signals controlling cellular, physical, and …

CD44, a multi-structural and multifunctional transmembrane glycoprotein, was initially
identified as a receptor for hyaluronan that participates in both physiological and …

After immunogenic challenge, infiltrating and dividing lymphocytes markedly increase lymph
node cellularity, leading to organ expansion,. Here we report that the physical elasticity of …

Podoplanin (PDPN) is a well-conserved, mucin-type transmembrane protein expressed in
multiple tissues during ontogeny and in adult animals, including the brain, heart, kidney …

In lymph nodes, fibroblastic reticular cells (FRCs) form a collagen-based reticular network
that supports migratory dendritic cells (DCs) and T cells and transports lymph. A hallmark of …

Podoplanin is a small membrane glycoprotein with a large number of O-glycoside chains
and therefore it belongs to mucin-type proteins. It can be found on the surface of many types …

The fundamental theory of Förster resonance energy transfer (FRET) was established in the
1940s. Its great power was only realized in the past 20 years after different techniques were …