Tissue and plasma proteomics for early stage cancer detection
The pursuit of novel and effective biomarkers is essential in the struggle against cancer,
which is a leading cause of mortality worldwide. Biomarkers can be used as specific …
which is a leading cause of mortality worldwide. Biomarkers can be used as specific …
Internal standard triggered-parallel reaction monitoring mass spectrometry enables multiplexed quantification of candidate biomarkers in plasma
JJ Kennedy, JR Whiteaker, RG Ivey, A Burian… - Analytical …, 2022 - ACS Publications
Despite advances in proteomic technologies, clinical translation of plasma biomarkers
remains low, partly due to a major bottleneck between the discovery of candidate …
remains low, partly due to a major bottleneck between the discovery of candidate …
Methods for the analysis and interpretation for rare variants associated with complex traits
With the advent of Next Generation Sequencing (NGS) technologies, whole genome and
whole exome DNA sequencing has become affordable for routine genetic studies. Coupled …
whole exome DNA sequencing has become affordable for routine genetic studies. Coupled …
[HTML][HTML] A plasma long noncoding RNA signature for early detection of lung cancer
Y Lin, Q Leng, M Zhan, F Jiang - Translational Oncology, 2018 - Elsevier
The early detection of lung cancer is a major clinical challenge. Long noncoding RNAs
(lncRNAs) have important functions in tumorigenesis. Plasma lncRNAs directly released …
(lncRNAs) have important functions in tumorigenesis. Plasma lncRNAs directly released …
[HTML][HTML] A plasma miRNA signature for lung cancer early detection
Q Leng, Y Lin, F Jiang, CJ Lee, M Zhan, HB Fang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The early detection of lung cancer continues to be a major clinical challenge. Using whole-
transcriptome next-generation sequencing to analyze lung tumor and the matched …
transcriptome next-generation sequencing to analyze lung tumor and the matched …
Fucosylation genes as circulating biomarkers for lung cancer
Abstract Purpose Fucosyltransferases (FUTs) catalyze fucosylation, which plays a central
role in biological processes. Aberrant fucosylation is associated with malignant …
role in biological processes. Aberrant fucosylation is associated with malignant …
A classifier integrating plasma biomarkers and radiological characteristics for distinguishing malignant from benign pulmonary nodules
Y Lin, Q Leng, Z Jiang, MA Guarnera… - … journal of cancer, 2017 - Wiley Online Library
Lung cancer is primarily caused by cigarette smoking and the leading cancer killer in the
USA and across the world. Early detection of lung cancer by low‐dose CT (LDCT) can …
USA and across the world. Early detection of lung cancer by low‐dose CT (LDCT) can …
A multiplex platform for the identification of ovarian cancer biomarkers
KLM Boylan, K Geschwind, JS Koopmeiners… - Clinical proteomics, 2017 - Springer
Background Currently, there are no FDA approved screening tools for detecting early stage
ovarian cancer in the general population. Development of a biomarker-based assay for early …
ovarian cancer in the general population. Development of a biomarker-based assay for early …
Molecular biology: marked progress
H Hoag - Nature, 2015 - nature.com
Molecular biology: Marked progress | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …
nature.com. You are using a browser version with limited support for CSS. To obtain the best …
Crucial considerations for pipelines to validate circulating biomarkers for breast cancer
R Ewaisha, CD Gawryletz… - Expert Review of …, 2016 - Taylor & Francis
Despite decades of progress in breast imaging, breast cancer remains the second most
common cause of cancer mortality in women. The rapidly proliferative breast cancers that …
common cause of cancer mortality in women. The rapidly proliferative breast cancers that …