Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
LB Shrestha, C Foster, W Rawlinson… - Reviews in Medical …, 2022 - Wiley Online Library
The first dominant SARS‐CoV‐2 Omicron variant BA. 1 harbours 35 mutations in its Spike protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon after its …
Z Cao, W Gao, H Bao, H Feng, S Mei… - … England Journal of …, 2023 - Mass Medical Soc
Background Nirmatrelvir–ritonavir has been authorized for emergency use by many countries for the treatment of coronavirus disease 2019 (Covid-19). However, the supply …
Objectives To characterize the clinical severity of covid-19 associated with the alpha, delta, and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …
Having adopted a dynamic zero-COVID strategy to respond to SARS-CoV-2 variants with higher transmissibility since August 2021, China is now considering whether, and for how …
J Yu, AY Collier, M Rowe, F Mardas… - … England Journal of …, 2022 - Mass Medical Soc
Neutralization of Omicron BA. 1 and BA. 2 Variants Although two doses of BNT162b2 vaccine produce immunity that wanes over time, the administration of a booster dose …
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19 and are especially important in high-risk individuals where vaccination is not an option …
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …