[HTML][HTML] Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective

S Salvioli, MS Basile, L Bencivenga, S Carrino… - Ageing Research …, 2023 - Elsevier
According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

Yearning for machine learning: applications for the classification and characterisation of senescence

BK Hughes, R Wallis, CL Bishop - Cell and Tissue Research, 2023 - Springer
Senescence is a widely appreciated tumour suppressive mechanism, which acts as a barrier
to cancer development by arresting cell cycle progression in response to harmful stimuli …

[HTML][HTML] Metal mixtures and DNA methylation measures of biological aging in American Indian populations

K Boyer, A Domingo-Relloso, E Jiang, K Haack… - Environment …, 2023 - Elsevier
Abstract Introduction Native American communities suffer disproportionately from elevated
metal exposures and increased risk for cardiovascular diseases and diabetes. DNA …

Genetic evidence for causal effects of socioeconomic, lifestyle, and cardiometabolic factors on epigenetic-age acceleration

L Kong, C Ye, Y Wang, T Hou, J Zheng… - The Journals of …, 2023 - academic.oup.com
Abstract GrimAge acceleration (GrimAgeAccel) and PhenoAge acceleration
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …

[HTML][HTML] Different aspects of aging in migraine

M Fila, E Pawlowska, J Szczepanska… - Aging and Disease, 2023 - ncbi.nlm.nih.gov
Migraine is a common neurological disease displaying an unusual dependence on age. For
most patients, the peak intensity of migraine headaches occurs in 20s and lasts until 40s, but …

[HTML][HTML] Epigenetic Reprogramming as a Key to Reverse Ageing and Increase Longevity

B Pereira, FP Correia, IA Alves, M Costa… - Ageing research …, 2024 - Elsevier
The pursuit for the fountain of youth has long been a fascination amongst scientists and
humanity. Ageing is broadly characterized by a cellular decline with increased susceptibility …

Forensic age estimation through a DNA methylation-based age prediction model in the Italian population: A pilot study

M Onofri, A Delicati, B Marcante, L Carlini… - International Journal of …, 2023 - mdpi.com
DNA methylation is one of the epigenetic marks which has been studied intensively in recent
years for age predicting purposes in the forensic area. In order to integrate age prediction …

A unified model of age-related cardiovascular disease

M Fossel, J Bean, N Khera, MG Kolonin - Biology, 2022 - mdpi.com
Simple Summary Age-related cardiovascular disease is the foremost cause of death
globally. Despite medical advances, we have been unable to stop or reverse the underlying …

Associations of epigenetic age acceleration with CVD risks across the lifespan: the Bogalusa Heart Study

X Sun, W Chen, AC Razavi, M Shi, Y Pan, C Li… - Basic to Translational …, 2024 - jacc.org
Although epigenetic age acceleration (EAA) might serve as a molecular signature of
childhood cardiovascular disease (CVD) risk factors and further promote midlife subclinical …

Eight weeks of physical training decreases 2 years of DNA methylation age of sedentary women

G da Silva Rodrigues, IHY Noma… - … Quarterly for Exercise …, 2024 - Taylor & Francis
Purpose: The acceleration of epigenetic age is a predictor of mortality and contributes to the
increase in chronic diseases. Adherence to a healthy lifestyle is a strategy to reduce …