Diabetes mellitus (DM), and its micro and macrovascular complications, is one of the biggest
challenges for world public health. Despite overall improvement in prevention, diagnosis …

Endothelial dysfunction is an early pathophysiological feature and independent predictor of
poor prognosis in most forms of cardiovascular diseases. Epidemiological studies report an …

Background Oxidative stress-induced vascular endothelial cell injury is a major factor in the
pathogenesis of atherosclerosis. Several evidences indicate that ellagic acid (EA), a …

Background: Polyphenols are bioactive compounds that can be found mostly in foods like
fruits, cereals, vegetables, dry legumes, chocolate and beverages such as coffee, tea and …

Population studies have shown a strong association between dietary intake of polyphenols
and reduced risk of cardiovascular disease. These associations have been confirmed to …

Endothelial dysfunction and insulin resistance are frequently comorbid states. Vasodilator
actions of insulin are mediated by phosphatidylinositol 3-kinase (PI3K)-dependent signaling …

Background Studies suggest cardioprotective benefits of dark chocolate containing cocoa.
Objective This study examines the acute effects of solid dark chocolate and liquid cocoa …

Background—Dark chocolate has potent antioxidant properties. Coronary atherosclerosis is
promoted by impaired endothelial function and increased platelet activation. Traditional risk …

Epidemiological evidence demonstrates that diets rich in fruit and vegetables promote
health, and attenuate, or delay, the onset of various diseases, including cardiovascular …

Cocoa products, which are rich sources of flavonoids, have been shown to reduce blood
pressure and the risk of cardiovascular disease. Dark chocolate contains saturated fat and is …