The influence of hormonal contraceptive use on HIV-1 transmission and disease progression

JM Baeten, L Lavreys… - Clinical infectious diseases, 2007 - academic.oup.com
Women account for nearly one-half of new human immunodeficiency virus type 1 (HIV-1)
infections worldwide, including the majority of infections in Africa. Biological and …

The future of HIV microbicides: challenges and opportunities

AB Garg, J Nuttall, J Romano - Antiviral Chemistry and …, 2009 - journals.sagepub.com
HIV microbicides are topical, self-administered products aimed at preventing or reducing
HIV infection in women and may represent the most promising strategy for combating the …

Evaluation of antiretrovirals in animal models of HIV infection

KKA Van Rompay - Antiviral research, 2010 - Elsevier
Animal models of HIV infection have played an important role in the development of
antiretroviral drugs. Although each animal model has its limitations and never completely …

Circuit theory of crossed Andreev reflection

JP Morten, A Brataas, W Belzig - Physical Review B—Condensed Matter and …, 2006 - APS
We consider transport in a three-terminal device attached to one superconducting and two
normal-metal terminals, using the circuit theory of mesoscopic superconductivity. We …

Gram-positive bacteria enhance HIV-1 susceptibility in Langerhans cells, but not in dendritic cells, via Toll-like receptor activation

Y Ogawa, T Kawamura, T Kimura, M Ito… - Blood, The Journal …, 2009 - ashpublications.org
Although numerous studies have shown a higher risk of acquiring HIV infection in the
presence of other sexually transmitted diseases, the biologic mechanisms responsible for …

Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives

T Wang, JF Kadow, Z Zhang, Z Yin, Q Gao, D Wu… - Bioorganic & medicinal …, 2009 - Elsevier
4-Fluoro-and 4-methoxy-1-(4-benzoylpiperazin-1-yl)-2-(1H-indol-3-yl) ethane-1, 2-dione (2
and 3, respectively) have been characterized as potent inhibitors of HIV-1 attachment that …

HIV sexual transmission and microbicides

KK Ariën, V Jespers, G Vanham - Reviews in medical virology, 2011 - Wiley Online Library
Pathogens often rely on the contacts between hosts for transmission. Most viruses have
adapted their transmission mechanisms to defined behaviours of their host (s) and have …

[HTML][HTML] High-mannose-specific deglycosylation of HIV-1 gp120 induced by resistance to cyanovirin-N and the impact on antibody neutralization

Q Hu, N Mahmood, RJ Shattock - Virology, 2007 - Elsevier
HIV-1 uses glycans on gp120 to occlude its highly immunogenic epitopes. To better
elucidate escape mechanisms of HIV-1 from carbohydrate-binding agents (CBA) and to …

[HTML][HTML] Preclinical assessments of vaginal microbicide candidate safety and efficacy

JA Fernández-Romero, N Teleshova… - Advanced drug delivery …, 2015 - Elsevier
Sexually transmitted infections like HIV, HPV, and HSV-2, as well as unplanned pregnancy,
take a huge toll on women worldwide. Woman-initiated multipurpose prevention …

Mucosal innate immunity as a determinant of HIV susceptibility

SM Iqbal, R Kaul - American journal of reproductive …, 2008 - Wiley Online Library
Most human immunodeficiency virus (HIV) is acquired during sex, across a mucosal
membrane. Despite many advances in our understanding of HIV pathogenesis, the initial …