Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by
ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory …

In recent years the importance of the localisation and trafficking of Toll-like receptors (TLRs)
and their adaptors within the cell has become apparent. Localisation and trafficking of both …

CD36 is a multi-ligand scavenger receptor present on the surface of a number of cells such
as platelets, monocytes/macrophages, endothelial and smooth muscle cells. Monocyte …

The sense of smell enables insects to recognize olfactory signals crucial for survival and
reproduction. In insects, odorant detection highly depends on the interplay of distinct …

The spleen is one of the major immunological sites for maintaining blood homeostasis.
Previous studies showed that heterogeneous splenic macrophage populations contribute in …

Cardiovascular disease, a leading cause of mortality in developed countries, is mainly
caused by atherosclerosis, a chronic inflammatory disease. Macrophages, which …

Accumulating evidence shows that many scavenger receptors (SR), including SR‐A,
MARCO and CD36, represent an important part of the innate immune defence by acting as …

Scavenger receptors constitute a large family of proteins that are structurally diverse and
participate in a wide range of biological functions. These receptors are expressed …

Phagocytosis, the engulfment of material by cells, is a highly conserved process that arose
before the development of multicellularity. Phagocytes have a key role in embryogenesis …

The innate immune system of insects relies on both humoral and cellular immune responses
that are mediated via activation of several signalling pathways. Haemocytes are the primary …