The insect SNMP gene family

RG Vogt, NE Miller, R Litvack, RA Fandino… - Insect biochemistry and …, 2009 - Elsevier
SNMPs are membrane proteins observed to associate with chemosensory neurons in
insects; in Drosophila melanogaster, SNMP1 has been shown to be essential for the …

Macrophage-derived upd3 cytokine causes impaired glucose homeostasis and reduced lifespan in Drosophila fed a lipid-rich diet

KJ Woodcock, K Kierdorf, CA Pouchelon, V Vivancos… - Immunity, 2015 - cell.com
Long-term consumption of fatty foods is associated with obesity, macrophage activation and
inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of …

Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer's disease

K Wilkinson, J El Khoury - International journal of Alzheimer's …, 2012 - Wiley Online Library
Alzheimer's disease (AD) is increasing in prevalence with the aging population. Deposition
of amyloid‐β (Aβ) in the brain of AD patients is a hallmark of the disease and is associated …

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

JJ Manning-Tobin, KJ Moore, TA Seimon… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—The scavenger receptors SR-A and CD36 have been implicated in macrophage
foam cell formation during atherogenesis and in the regulation of inflammatory signaling …

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

TK Means, E Mylonakis, E Tampakakis… - Journal of Experimental …, 2009 - rupress.org
Receptors involved in innate immunity to fungal pathogens have not been fully elucidated.
We show that the Caenorhabditis elegans receptors CED-1 and C03F11. 3, and their …

[HTML][HTML] Mechanisms of cell signaling by the scavenger receptor CD36: implications in atherosclerosis and thrombosis

RL Silverstein, W Li, YM Park… - Transactions of the …, 2010 - ncbi.nlm.nih.gov
CD36 is a multifunctional membrane receptor present on mononuclear phagocytes,
platelets, and other cells that serves as a scavenger receptor for oxidized phospholipids …

CD36: implications in cardiovascular disease

M Febbraio, RL Silverstein - The international journal of biochemistry & cell …, 2007 - Elsevier
CD36 is a broadly expressed membrane glycoprotein that acts as a facilitator of fatty acid
uptake, a signaling molecule, and a receptor for a wide range of ligands, including apoptotic …

A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling

DJ Kennedy, S Kuchibhotla, KM Westfall… - Cardiovascular …, 2011 - academic.oup.com
Aims Obesity and hyperlipidaemia are associated with insulin resistance (IR); however, the
mechanisms responsible remain incompletely understood. Pro-atherogenic hyperlipidaemic …

[HTML][HTML] Tlr2 is critical for diet-induced metabolic syndrome in a murine model

RW Himes, CW Smith - The FASEB Journal, 2010 - ncbi.nlm.nih.gov
Obesity and its associated comorbidities, termed metabolic syndrome, are increasingly
prevalent, and they pose a serious threat to the health of individuals and populations. Gene …

[HTML][HTML] Phagocytosis in Drosophila: From molecules and cellular machinery to physiology

C Melcarne, B Lemaitre, E Kurant - Insect biochemistry and molecular …, 2019 - Elsevier
Phagocytosis is an evolutionarily conserved mechanism that plays a key role in both host
defence and tissue homeostasis in multicellular organisms. A range of surface receptors …