CD36 is a multifunctional immuno-metabolic receptor with many ligands. One of its
physiological functions in the heart is the high-affinity uptake of long-chain fatty acids (FAs) …

Corals form an endosymbiotic relationship with the dinoflagellate algae Symbiodiniaceae,
but ocean warming can trigger algal loss, coral bleaching and death, and the degradation of …

Innate immunity is the first-line defense against pathogens and relies on phagocytes,
soluble components, and cell-surface and cytosolic pattern recognition receptors. Despite …

Mycobacterium tuberculosis (Mtb) signals through Toll-like receptor 2 (TLR2) to regulate
antigen presenting cells (APCs). Mtb lipoproteins, including LpqH, LprA, LprG and PhoS1 …

CD36 is a scavenger receptor that binds multiple ligands, including phosphatidyl serine
(PS). Although CD36–mice do not have a bleeding diathesis, we show here that they do …

Pattern recognition receptors (PRRs) are generally recognized as the initiators of all immune
responses. PRRs bind molecular patterns associated with microorganisms or endogenous …

Macrophages are central to the initiation and progression of atherosclerosis and thus can be
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …

Staphylococcus aureus is both a colonizer of humans and a cause of severe invasive
infections. Although the genetic basis for phenotype switching from colonizing to invasive …

From early on in evolution, organisms have had to protect themselves from pathogens.
Mechanisms for discriminating “self” from “non‐self” evolved to accomplish this task …

Mycobacterium tuberculosis infects primarily macrophages in the lungs. Infected
macrophages are surrounded by other immune cells in well organised structures called …