Oxidized high-density lipoprotein promotes CD36 palmitoylation and increases lipid uptake in macrophages

Y Zhang, D Dong, X Xu, H He, Y Zhu, T Lei… - Journal of Biological …, 2022 - ASBMB
Oxidized high-density lipoprotein (oxHDL) reduces the ability of cells to mediate reverse
cholesterol transport and also shows atherogenic properties. Palmitoylation of cluster of …

The function of TLR2 during staphylococcal diseases

B Fournier - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
Staphylococcus aureus is a versatile pathogen causing a wide range of infections. It has
been a major threat both in hospitals and in the community for decades. S. aureus is a …

Steroid Hormone Signaling Is Essential to Regulate Innate Immune Cells and Fight Bacterial Infection in Drosophila

JC Regan, AS Brandão, AB Leitão… - PLoS …, 2013 - journals.plos.org
Coupling immunity and development is essential to ensure survival despite changing
internal conditions in the organism. Drosophila metamorphosis represents a striking …

Pattern recognition receptors and their role in innate immunity: focus on microbial protein ligands

T Areschoug, S Gordon - Trends in innate immunity, 2008 - karger.com
Antigen-presenting cells, such as macrophages and dendritic cells, represent a central and
important part of the immune defence against invading microorganisms, as they participate …

A novel lipopeptide from skin commensal activates TLR2/CD36-p38 MAPK signaling to increase antibacterial defense against bacterial infection

D Li, H Lei, Z Li, H Li, Y Wang, Y Lai - PloS one, 2013 - journals.plos.org
Staphylococcus epidermidis (S. epidermidis) plays important protective roles by directly
producing or by stimulating hosts to produce antimicrobial peptides (AMPs) against …

Scavenger receptor B2, a type III membrane pattern recognition receptor, senses LPS and activates the IMD pathway in crustaceans

XZ Shi, MC Yang, XL Kang, YX Li… - Proceedings of the …, 2023 - National Acad Sciences
The immune deficiency (IMD) pathway is critical for elevating host immunity in both insects
and crustaceans. The IMD pathway activation in insects is mediated by peptidoglycan …

Dectin‐1 promotes fungicidal activity of human neutrophils

AD Kennedy, JA Willment, DW Dorward… - European journal of …, 2007 - Wiley Online Library
Human polymorphonuclear leukocytes (PMN) are a first line of defense against fungal
infections. PMN express numerous pattern recognition receptors (PRR) that facilitate …

Scavenger receptor CD36 expression contributes to adipose tissue inflammation and cell death in diet-induced obesity

L Cai, Z Wang, A Ji, JM Meyer… - PloS one, 2012 - journals.plos.org
Objective The enlarged adipose tissue in obesity is characterized by inflammation, including
the recruitment and infiltration of macrophages and lymphocytes. The objective of this study …

SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

L Cai, A Ji, FC de Beer, LR Tannock… - The Journal of …, 2008 - Am Soc Clin Investig
Septic shock results from an uncontrolled inflammatory response, mediated primarily by
LPS. Cholesterol transport plays an important role in the host response to LPS, as LPS is …

CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria

LK Erdman, G Cosio, AJ Helmers, D Gowda… - The Journal of …, 2009 - journals.aai.org
CD36 participates in macrophage internalization of a variety of particles, and has been
implicated in inflammatory responses to many of these ligands. To what extent CD36 …