Viral nanoparticles (VNPs) are self-assembling, adaptable delivery systems for vaccines and
other therapeutic agents used in a variety of biomedical applications. The potential of …

RNA-based therapeutics have emerged as promising approaches to modulate gene
expression and generate therapeutic proteins or antigens capable of inducing immune …

Direct and efficient delivery of functional payloads such as chemotherapy drugs, siRNA, or
small-molecule inhibitors into the cytoplasm, bypassing the endo/lysosomal trapping, is a …

The effectiveness of messenger RNA (mRNA) vaccines, especially those designed for
COVID-19, relies heavily on sophisticated delivery systems that ensure efficient delivery of …

Cardiomyopathies are among the major triggers of heart failure, but their clinical and genetic
complexity have hampered our understanding of these disorders and delayed the …

Cancer nanovaccines represent a promising frontier in cancer immunotherapy, utilizing
nanotechnology to augment traditional vaccine efficacy. This review comprehensively …

Central nervous system (CNS) diseases are currently a major challenge in medicine. One
reason is the presence of the blood–brain barrier, which is a significant limitation for …

Monogenic disorders refer to a group of human diseases caused by mutations in single
genes. While disease-modifying therapies have offered some relief to symptoms and …

Simple Summary Today, a significant issue in treating the most common cancers is their
resistance to current treatment options like chemotherapy, radiotherapy, or immunotherapy …

The dramatic effectiveness of recent mRNA (mRNA)-based COVID vaccines delivered in
lipid nanoparticles has highlighted the promise of mRNA therapeutics in general. In this …