[HTML][HTML] Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

[HTML][HTML] Systems pharmacology approaches in herbal medicine research: a brief review

M Lee, H Shin, M Park, A Kim, S Cha, H Lee - BMB reports, 2022 - ncbi.nlm.nih.gov
Herbal medicine, a multi-component treatment, has been extensively practiced for treating
various symptoms and diseases. However, its molecular mechanism of action on the human …

[HTML][HTML] ACE2 protein expression in lung tissues of severe COVID-19 infection

A Gheware, A Ray, D Rana, P Bajpai, A Nambirajan… - Scientific reports, 2022 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells …

[HTML][HTML] Human-derived air–liquid interface cultures decipher Alzheimer's disease–SARS-CoV-2 crosstalk in the olfactory mucosa

MA Shahbaz, S Kuivanen, R Lampinen… - Journal of …, 2023 - Springer
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …

Microplastics dysregulate innate immunity in the SARS-CoV-2 infected lung

CR Bishop, K Yan, W Nguyen, DJ Rawle… - Frontiers in …, 2024 - frontiersin.org
Introduction Global microplastic (MP) pollution is now well recognized, with humans and
animals consuming and inhaling MPs on a daily basis, with a growing body of concern …

[HTML][HTML] Bacterial Biomarkers of the Oropharyngeal and Oral Cavity during SARS-CoV-2 Infection

W Bourumeau, K Tremblay, G Jourdan, C Girard… - Microorganisms, 2023 - mdpi.com
(1) Background: Individuals with COVID-19 display different forms of disease severity and
the upper respiratory tract microbiome has been suggested to play a crucial role in the …

Meta-analysis of transcriptomic data from lung autopsy and cellular models of SARS-CoV-2 infection

NA Cadore, VO Lord, M Recamonde-Mendoza… - Biochemical …, 2024 - Springer
Severe COVID-19 is a systemic disorder involving excessive inflammatory response,
metabolic dysfunction, multi-organ damage, and several clinical features. Here, we …

The landscape of differential splicing and transcript alternations in severe COVID‐19 infection

SB Mukherjee, S Mukherjee, R Detroja… - The FEBS …, 2023 - Wiley Online Library
Viral infections can modulate the widespread alternations of cellular splicing, favouring viral
replication within the host cells by overcoming host immune responses. However, how …

SARS-CoV-2 viral replication persists in the human lung for several weeks after symptom onset

M Tomasicchio, S Jaumdally, L Wilson… - American Journal of …, 2024 - atsjournals.org
Rationale: In the upper respiratory tract, replicating (culturable) severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is recoverable for∼ 4–8 days after symptom onset …

[HTML][HTML] Understanding the neurological implications of acute and long COVID using brain organoids

L García-González, A Martí-Sarrias… - Disease Models & …, 2023 - journals.biologists.com
As early as in the acute phase of the coronavirus disease 2019 (COVID-19) pandemic, the
research community voiced concerns about the long-term implications of infection. Severe …