Microglia represent the first line of immune feedback in the brain. Beyond immune
surveillance, they are essential for maintaining brain homeostasis. Recent research has …

A major immunopathological feature of Coronavirus disease-2019 (COVID-19) is excessive
inflammation in the form of “cytokine storm”. The storm is characterized by injurious levels of …

The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective
IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 …

Introduction Chimeric antigen receptor (CAR) T-cell is among the most prevalent
approaches that act by directing T-cells toward cancer; however, they need to be optimized …

Amyotrophic lateral sclerosis (ALS) is the most prevalent motor neuron disorder worldwide.
In ALS, progressing disease can result from misfolding and aggregation of superoxide …

Neuropsychiatric disorders denote a broad range of illnesses involving neurology and
psychiatry. These disorders include depressive disorders, anxiety, schizophrenia, bipolar …

Interferon (IFN) has been highlighted in several randomized controlled trials as an attractive
therapeutic candidate based plausible mode of action, suppressed response in severe …

Recent studies have established the role of bacteria including Streptococcus pneumoniae,
Helicobacter pylori, Chlamydia pneumonia, Mycobacterium tuberculosis, and …

Chest X-ray (CXR), computed tomography (CT), and positron emission tomography–
computed tomography (PET-CT) are noninvasive imaging techniques widely used in human …

Finding cytokine storm initiator factors associated with uncontrolled inflammatory immune
response is necessary in COVID-19 patients. The aim was the identification of Fas/Fas …