The global burden of coeliac disease: opportunities and challenges
Coeliac disease is a systemic disorder characterized by immune-mediated enteropathy,
which is caused by gluten ingestion in genetically susceptible individuals. The clinical …
which is caused by gluten ingestion in genetically susceptible individuals. The clinical …
Society for the Study of Celiac Disease position statement on gaps and opportunities in coeliac disease
MI Pinto-Sanchez, JA Silvester, B Lebwohl… - Nature Reviews …, 2021 - nature.com
Progress has been made in understanding coeliac disease, a relatively frequent and
underappreciated immune-mediated condition that occurs in genetically predisposed …
underappreciated immune-mediated condition that occurs in genetically predisposed …
Gut microbiota dysbiosis in systemic lupus erythematosus: novel insights into mechanisms and promising therapeutic strategies
Q Pan, F Guo, Y Huang, A Li, S Chen, J Chen… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that was traditionally
thought to be closely related to genetic and environmental risk factors. Although treatment …
thought to be closely related to genetic and environmental risk factors. Although treatment …
The emerging role of the small intestinal microbiota in human health and disease
RAAA Ruigrok, RK Weersma, A Vich Vila - Gut microbes, 2023 - Taylor & Francis
The human gut microbiota continues to demonstrate its importance in human health and
disease, largely owing to the countless number of studies investigating the fecal microbiota …
disease, largely owing to the countless number of studies investigating the fecal microbiota …
The emerging roles of bacterial proteases in intestinal diseases
Proteases are an evolutionarily conserved family of enzymes that degrade peptide bonds
and have been implicated in several common gastrointestinal (GI) diseases. Although …
and have been implicated in several common gastrointestinal (GI) diseases. Although …
A human autoimmune organoid model reveals IL-7 function in coeliac disease
In vitro models of autoimmunity are constrained by an inability to culture affected epithelium
alongside the complex tissue-resident immune microenvironment. Coeliac disease (CeD) is …
alongside the complex tissue-resident immune microenvironment. Coeliac disease (CeD) is …
Causal association between celiac disease and inflammatory bowel disease: A two-sample bidirectional Mendelian randomization study
S Yuan, JH Kim, P Xu, Z Wang - Frontiers in Immunology, 2023 - frontiersin.org
Background An epidemiological link between celiac disease (CeD) and inflammatory bowel
disease (IBD) has been well established recently. In this study, Mendelian randomization …
disease (IBD) has been well established recently. In this study, Mendelian randomization …
Co-factors, microbes, and immunogenetics in celiac disease to guide novel approaches for diagnosis and treatment
EF Verdu, D Schuppan - Gastroenterology, 2021 - Elsevier
Celiac disease (CeD) is a frequent immune-mediated disease that affects not only the small
intestine but also many extraintestinal sites. The role of gluten proteins as dietary triggers …
intestine but also many extraintestinal sites. The role of gluten proteins as dietary triggers …
Immunopathogenesis and environmental triggers in coeliac disease
A Levescot, G Malamut, N Cerf-Bensussan - Gut, 2022 - gut.bmj.com
Coeliac disease (CD) is a frequent immune enteropathy induced by gluten in genetically
predisposed individuals. Its pathogenesis has been extensively studied and CD has …
predisposed individuals. Its pathogenesis has been extensively studied and CD has …