Alphaherpesvirus genomics: past, present and future

CV Kuny, ML Szpara - Current issues in molecular biology, 2021 - mdpi.com
Alphaherpesviruses, as large double-stranded DNA viruses, were long considered to be
genetically stable and to exist in a homogeneous state. Recently, the proliferation of high …

Current ocular microbiome investigations limit reproducibility and reliability: Critical review and opportunities

EM Scott, AC Lewin, ML Leis - Veterinary Ophthalmology, 2021 - Wiley Online Library
Enthusiasm for research describing microbial communities using next‐generation
sequencing (NGS) has outpaced efforts to standardize methodology. Without consistency in …

[HTML][HTML] Phylogenomic assessment of 23 equid alphaherpesvirus 1 isolates obtained from USA-based equids

U Emelogu, AC Lewin, UBR Balasuriya, CC Liu… - Virology journal, 2023 - Springer
Abstract Background Equid alphaherpesvirus 1 (EHV-1) is a global viral pathogen of
domestic equids which causes reproductive, respiratory and neurological disease. Few …

[HTML][HTML] Full Viral Genome Sequencing and Phylogenomic Analysis of Feline Herpesvirus Type 1 (FHV-1) in Cheetahs (Acinonyx jubatus)

ME Marino, MA Mironovich, NE Ineck, SB Citino… - Viruses, 2021 - mdpi.com
Feline herpesvirus type 1 (FHV-1) is endemic in captive cheetahs and sporadically causes
devastating disease. Modified live vaccines (MLV), intended for use in domestic cats, are …

[HTML][HTML] Surveillance for feline herpesvirus type 1 mutation and development of resistance in cats treated with antiviral medications

AC Lewin, NE Ineck, MA Mironovich… - Frontiers in Veterinary …, 2023 - frontiersin.org
Feline herpesvirus type 1 (FHV-1) commonly causes ocular surface disease in cats and is
treated with antiviral medications targeting viral DNA polymerase (UL30/42). Herein, we …

[HTML][HTML] Phylogenomic analysis of global isolates of canid alphaherpesvirus 1

AC Lewin, LM Coghill, M Mironovich, CC Liu, RT Carter… - Viruses, 2020 - mdpi.com
Canid alphaherpesvirus 1 (CHV-1) is a widespread pathogen of dogs with multiple
associated clinical signs. There has been limited prior investigation into the genomics and …

[HTML][HTML] First report of molecular epidemiology and phylogenetic characteristics of feline herpesvirus (FHV-1) from naturally infected cats in Kunshan, China

S Kim, Y Cheng, Z Fang, Q Zhongqi, Y Weidong… - Virology Journal, 2024 - Springer
Background Feline herpesvirus type 1 (FHV-1) is a life threatening highly contagious virus in
cats and typically causes upper respiratory tract infections as well as conjunctival and …

Genomic analysis for virulence determinants in feline herpesvirus type-1 isolates

AC Lewin, LM Coghill, GJ McLellan, E Bentley… - Virus genes, 2020 - Springer
Abstract Feline herpesvirus type 1 (FHV-1) is a widespread cause of respiratory and ocular
disease in domestic cats. A spectrum of disease severity is observed in host animals, but …

A review of evidence‐based management of infectious ocular surface disease in shelter‐housed domestic cats

AC Lewin, SK Hicks, RT Carter - Veterinary Ophthalmology, 2023 - Wiley Online Library
Infectious ocular surface disease (IOSD) is a common problem in shelter‐housed domestic
cats and has a widespread negative impact on animal welfare. While the common …

Complete genome sequencing and assessment of mutation-associated protein dynamics of the first Indian bovine ephemeral fever virus (BEFV) isolate

S Pyasi, A Gupta, NR Hegde, D Nayak - Veterinary Quarterly, 2021 - Taylor & Francis
Background Bovine ephemeral fever (BEF) is a re-emerging disease caused by bovine
ephemeral fever virus (BEFV). Although it poses a huge economic threat to the livestock …