Increasing time-to-treatment for lung cancer: are we going backward?

Z Muslim, S Stroever, SS Razi, K Poulikidis… - The Annals of Thoracic …, 2023 - Elsevier
Background Treatment delays in lung cancer care in the United States may be attributable to
a diverse range of patient, provider, and institutional factors, the precise contributions of …

Next Generation Sequencing of Advanced Non–Small Cell Lung Cancer: Utilization Based on Race and Impact on Survival

A Al-Ahmadi, F Ardeshir-Larijani, P Fu, S Cao… - Clinical Lung Cancer, 2021 - Elsevier
Background Next generation sequencing (NGS) of tumor of patients with advanced non–
small cell lung cancer (NSCLC) is now a standard of care that informs the clinician on the …

Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based …

J Remon, A Swalduz, D Planchard, S Ortiz-Cuaran… - PLoS …, 2020 - journals.plos.org
Circulating tumor DNA (ctDNA)-based molecular profiling is rapidly gaining traction in
clinical practice of advanced cancer patients with multi-gene next-generation sequencing …

Testing for EGFR Variants in Pleural and Pericardial Effusion Cell-Free DNA in Patients With Non–Small Cell Lung Cancer

KWC Lee, MSC Li, W Gai, YM Lau, AKC Chan… - JAMA …, 2023 - jamanetwork.com
Importance Molecular testing in non–small cell lung cancer (NSCLC) is commonly limited by
inadequate tumor sample. Plasma cell-free DNA (cfDNA) genotyping as a complementary …

[HTML][HTML] lncRNA AWPPH promotes proliferation and inhibits apoptosis of non‑small cell lung cancer cells by activating the Wnt/β‑catenin signaling pathway

Z Song, J Du, L Zhou, B Sun - Molecular Medicine …, 2019 - spandidos-publications.com
AWPPH is a newly discovered long non‑coding (lnc) RNA that serves an oncogenic role in
the development of several types of cancer; however, its involvement in non‑small cell lung …

Molecular testing for lung adenocarcinoma: Is it time to adopt a “plasma‐first” approach?

M Makarem, NB Leighl - Cancer, 2020 - Wiley Online Library
There is growing evidence that plasma cell‐free DNA testing can aid in the diagnosis of
targetable alterations at diagnosis in patients with advanced nonsquamous lung carcinoma …

[HTML][HTML] EGFR testing patterns and detection of EGFR exon 20 insertions in the United States

HM Lin, Y Yin, V Crossland, Y Wu, SHI Ou - JTO clinical and research …, 2022 - Elsevier
Introduction EGFR exon 20 insertions (EGFRex20ins) are a diverse set of mutations in
NSCLC that are refractory to tyrosine kinase inhibitors. We describe real-world …

Effect of a collaboration between a health plan, oncology practice, and comprehensive genomic profiling company from the payer perspective

M Reitsma, J Fox, PV Borre, M Cavanaugh… - Journal of managed …, 2019 - jmcp.org
BACKGROUND: Comprehensive genomic profiling (CGP) is a next-generation sequencing-
based methodology that detects 4 classes of genomic alterations, as well as gene signature …

EGFR testing and erlotinib use in non-small cell lung cancer patients in Kentucky

KL Larson, B Huang, Q Chen, T Tucker, M Schuh… - PloS one, 2020 - journals.plos.org
This study determined the frequency and factors associated with EGFR testing rates and
erlotinib treatment as well as associated survival outcomes in patients with non small cell …

[PDF][PDF] MiR-760 inhibits the progression of non-small cell lung cancer through blocking ROS1/Ras/Raf/MEK/ERK pathway

W Wang, B He - Biosci Rep, 2020 - scholar.archive.org
The purpose of this study was to investigate the role of miR-760 in non-small cell lung
cancer (NSCLC), as well as relevant molecular mechanisms. Expression patterns of miR …