Epstein-Barr virus: a paradigm for persistent infection–for real and in virtual reality

DA Thorley-Lawson, KA Duca, M Shapiro - Trends in immunology, 2008 - cell.com
The really interesting thing about herpesviruses is that they can establish lifelong persistant
infections in immunocompetent hosts. At first glance, they would seem to have very different …

Epstein-Barr virus: the path from latent to productive infection

YF Chiu, B Sugden - Annual review of virology, 2016 - annualreviews.org
The intrinsic properties of different viruses have driven their study. For example, the capacity
for efficient productive infection of cultured cells by herpes simplex virus 1 has made it a …

Studying Epstein–Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice

T Yasuda, T Wirtz, B Zhang… - Cold Spring Harbor …, 2013 - symposium.cshlp.org
Epstein–Barr virus (EBV) is a γ herpes virus endemic in humans and transforming human B
lymphocytes. It causes a variety of human pathologies ranging from infectious …

Role of cytotoxic T lymphocytes in Epstein-Barr virus-associated diseases

R Khanna, SR Burrows - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Adaptation of persistent infection within the cells of the immune system is a unique
characteristic of gamma herpes viruses. A classic example of this is Epstein-Barr virus …

Efficient replication of Epstein–Barr virus in stratified epithelium in vitro

RM Temple, J Zhu, L Budgeon… - Proceedings of the …, 2014 - National Acad Sciences
Epstein–Barr virus is a ubiquitous human herpesvirus associated with epithelial and
lymphoid tumors. EBV is transmitted between human hosts in saliva and must cross the oral …

A model for persistent infection with Epstein-Barr virus: the stealth virus of human B cells

DA Thorley-Lawson, GJ Babcock - Life sciences, 1999 - Elsevier
Most adult humans are infected benignly and for life with the herpesvirus Epstein-Barr virus.
EBV has been a focus of research because of its status as a candidate tumor virus for a …

Persistent γ-herpesvirus infections: What can we learn from an experimental mouse model?

MA Blackman, E Flaño - The Journal of experimental medicine, 2002 - rupress.org
The human-herpesviruses, EBV (or HHV-4) and Kaposi's sarcoma-associated herpesvirus
(KSHV or HHV-8) are oncogenic viruses that induce a readily controlled lytic infection …

Epstein–Barr virus and infectious mononucleosis: what students can teach us

AB Rickinson, CP Fox - The Journal of infectious diseases, 2013 - academic.oup.com
Herpes viruses are a large family of agents whose members have long coevolutionary
histories with their natural hosts. The product of that coevolution is a virus-host balance …

[HTML][HTML] The immune response to Epstein–Barr virus

MFC Callan - Microbes and infection, 2004 - Elsevier
Epstein–Barr virus is a gammaherpes virus that establishes persistent infection in the
majority of humans. Despite the potent oncogenic potential of the virus it is relatively rarely …

Humanized mouse models for Epstein Barr virus infection

C Münz - Current opinion in virology, 2017 - Elsevier
It is essential for the human immune system to control Epstein Barr virus (EBV), because this
common human γ-herpesvirus efficiently spreads through the human population with more …