There is an intense interplay between HIV and the immune system, and the literature is
replete with studies describing various immunological phenomena associated with HIV …

Recent studies suggest that the pathogenesis of HIV infection and AIDS involves two distinct
phases. During acute infection, massive depletion of CD4+ CCR5+ memory T cells within …

Recent advances in the immunology, pathogenesis, and prevention of human
immunodeficiency virus (HIV) infection continue to reveal clues to the mechanisms involved …

HIV is a disease in which the original clinical observations of severe opportunistic infections
gave the first clues regarding the underlying pathology, namely that HIV is essentially an …

Abstract 22 years ago, the first cases of an acquired immunodeficiency syndrome afflicting
young, homosexual American men were reported, heralding what we now know to be the …

The rate of progression of HIV disease may be substantially different among HIV-infected
individuals. Following infection of the host with any virus, the delicate balance between virus …

In the absence of antiretroviral treatment, HIV-1 establishes a chronic infection that is
marked by the progressive depletion of CD4+ T-cells. Of all the viral infections that afflict …

Recent progress in HIV-1 and SIV pathogenesis has revealed that mucosal tissues, primarily
the gastrointestinal tract, are major sites for early viral replication and CD4+ T-cell …

▪ Abstract In the absence of antiretroviral treatment, HIV-1 establishes a chronic, progressive
infection of the human immune system that invariably, over the course of years, leads to its …

Human immunodeficiency virus (HIV) infection is generally characterized by inefficient viral
transmission; an acute phase of intense viral replication and dissemination to lymphoid …