[HTML][HTML] Idiopathic pulmonary fibrosis and the role of genetics in the era of precision medicine

A Alonso-Gonzalez, E Tosco-Herrera… - Frontiers in …, 2023 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, rare progressive lung disease, characterized
by lung scarring and the irreversible loss of lung function. Two anti-fibrotic drugs, nintedanib …

[HTML][HTML] Genetics in idiopathic pulmonary fibrosis pathogenesis, prognosis, and treatment

A Kaur, SK Mathai, DA Schwartz - Frontiers in medicine, 2017 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia (IIP), is characterized by irreversible scarring of the lung parenchyma and …

Genetics of idiopathic pulmonary fibrosis: from mechanistic pathways to personalised medicine

P Spagnolo, V Cottin - Journal of medical genetics, 2017 - jmg.bmj.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and ultimately fatal disorder for
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …

Recent advances in the genetics of idiopathic pulmonary fibrosis

P Spagnolo, JS Lee - Current Opinion in Pulmonary Medicine, 2023 - journals.lww.com
Recent advances in the genetics of idiopathic pulmonary fibr... : Current Opinion in Pulmonary
Medicine Recent advances in the genetics of idiopathic pulmonary fibrosis : Current Opinion …

Candidate genes of idiopathic pulmonary fibrosis: current evidence and research

W Zhou, Y Wang - The application of clinical genetics, 2016 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a group of common and lethal forms of idiopathic
interstitial pulmonary disease. IPF is characterized by a progressive decline in lung function …

Genetics in idiopathic pulmonary fibrosis: a clinical perspective

SA Papiris, C Kannengiesser, R Borie, L Kolilekas… - Diagnostics, 2022 - mdpi.com
Background: Unraveling the genetic background in a significant proportion of patients with
both sporadic and familial IPF provided new insights into the pathogenic pathways of …

Genetic background of idiopathic pulmonary fibrosis

S Santangelo, S Scarlata, A Zito, D Chiurco… - Expert review of …, 2013 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by
progressive fibrosing interstitial pneumonia. The histological pattern, which displays dense …

Beyond the diagnosis of idiopathic pulmonary fibrosis; the growing role of systems biology and stratified medicine

TM Maher - Current Opinion in Pulmonary Medicine, 2013 - journals.lww.com
Use of molecular research techniques in large populations of well-phenotyped patients is
leading to major advances in understanding of IPF. As new treatments for IPF emerge, it is to …

[HTML][HTML] Idiopathic pulmonary fibrosis is a complex genetic disorder

DA Schwartz - Transactions of the American Clinical and …, 2016 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a complex, heterogeneous genetic disorder that is
associated with rare and common sequence variants in many genes (MUC5B, SFTPC …

Evolving genomic approaches to idiopathic pulmonary fibrosis: moving beyond genes

DJ Kass, N Kaminski - Clinical and translational science, 2011 - Wiley Online Library
A little more than 10 years ago, the completed sequencing of the human genome boldly
promised to usher in an era of enhanced understanding and accelerated development of …