Identification of Bacterial Strains and Development of anmRNA-Based Vaccine to Combat Antibiotic Resistance in Staphylococcus aureus via In Vitro and In Silico …

M Naveed, M Waseem, T Aziz, J Hassan, SI Makhdoom… - Biomedicines, 2023 - mdpi.com
The emergence of antibiotic-resistant microorganisms is a significant concern in global
health. Antibiotic resistance is attributed to various virulent factors and genetic elements …

In silico analysis for identifying potential vaccine candidates against Staphylococcus aureus

S Delfani, AAI Fooladi, AM Mobarez… - Clinical and …, 2015 - synapse.koreamed.org
Purpose Staphylococcus aureus is one of the most important causes of nosocomial and
community-acquired infections. The increasing incidence of multiple antibiotic-resistant S …

Development of a Conserved Chimeric Vaccine for Induction of Strong Immune Response against Staphylococcus aureus Using Immunoinformatics Approaches

R Chatterjee, P Sahoo, SR Mahapatra, J Dey, M Ghosh… - Vaccines, 2021 - mdpi.com
Staphylococcus aureus is one of the most notorious Gram-positive bacteria with a very high
mortality rate. The WHO has listed S. aureus as one of the ESKAPE pathogens requiring …

Design of Staphylococcus aureus New Vaccine Candidates with B and T Cell Epitope Mapping, Reverse Vaccinology, and Immunoinformatics

MA Soltan, D Magdy, SM Solyman… - OMICS: A Journal of …, 2020 - liebertpub.com
An effective vaccine against Staphylococcus aureus infection is a major planetary heath
priority, particularly with increasing antibiotic resistance worldwide. Previous efforts for a …

Genome-Based Multi-Antigenic Epitopes Vaccine Construct Designing against Staphylococcus hominis Using Reverse Vaccinology and Biophysical Approaches

M Nawaz, A Ullah, AI Al-Harbi, MU Haq, AR Hameed… - Vaccines, 2022 - mdpi.com
Staphylococcus hominis is a Gram-positive bacterium from the staphylococcus genus; it is
also a member of coagulase-negative staphylococci because of its opportunistic nature and …

Designing a novel chimeric multi-epitope vaccine subunit against Staphylococcus argenteus through artificial intelligence approach integrating pan-genome analysis …

M Naveed, S Mahmood, T Aziz, A Azeem… - Journal of …, 2023 - Taylor & Francis
Staphylococcus argenteus is a newly identified pathogen that causes respiratory tract
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …

Immunoinformatics analysis and in silico designing of a novel multi-epitope peptide vaccine against Staphylococcus aureus

N Hajighahramani, N Nezafat, M Eslami… - Infection, Genetics and …, 2017 - Elsevier
Staphylococcus aureus is a pathogen that causes a variety of infections in humans.
Methicillin-resistant S. aureus, which is an antibiotic-resistant form, is responsible for …

Staphylococcus aureus Putative Vaccines Based on the Virulence Factors: A Mini-Review

B Mirzaei, R Babaei, H Zeighami, M Dadar… - Frontiers in …, 2021 - frontiersin.org
Since the 1960s, the frequency of methicillin-resistant Staphylococcus aureus as a recurrent
cause of nosocomial infections has increased. Since multidrug-resistant Staphylococcus has …

Development of a novel circular mRNA vaccine of six protein combinations against Staphylococcus aureus

F Zhu, S Ma, H Wen, M Rao, P Zhang… - Journal of …, 2023 - Taylor & Francis
Staphylococcus aureus is an extraordinarily versatile pathogen, which is currently the most
common cause of nosocomial and community infections. Considering that increased …

The epidemiological and pangenome landscape of Staphylococcus aureus and identification of conserved novel candidate vaccine antigens

K Naz, N Ullah, A Naz, S Irum, HA Dar… - Current …, 2022 - ingentaconnect.com
Background and Objective: Staphylococcus aureus (S. aureus) is a gram-positive bacterium
and one of the major nosocomial pathogens. It has the ability to acquire resistance against …