Biobanks facilitate genome-wide association studies (GWASs), which have mapped
genomic loci across a range of human diseases and traits. However, most biobanks are …

Genome-wide association studies (GWAS) have made impactful discoveries for complex
diseases, often by amassing very large sample sizes. Yet, GWAS of many diseases remain …

Background The remarkable growth of genome-wide association studies (GWAS) has
created a critical need to experimentally validate the disease-associated variants, 90% of …

One goal of genomic medicine is to uncover an individual's genetic risk for disease, which
generally requires data connecting genotype to phenotype, as done in genome-wide …

The advent of the first wave of genome-wide association studies (GWAS) provided a new
conceptual framework in the search for variants underlying common disorders: a massive …

The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …

Genome-wide association studies (GWAS) have identified thousands of genetic variants
linked to the risk of human disease. However, GWAS have so far remained largely …

Candidate gene and genome-wide association studies (GWAS) have identified genetic
variants that modulate risk for human disease; many of these associations require further …

Over the past 15 years, genome-wide association studies (GWASs) have generated a
wealth of new information. Larger samples sizes, refined phenotypes and higher-resolution …

Most common diseases and quantitative traits are heritable: determined in part by genetic
variation within the population. The inheritance is typically polygenic in that combined effects …