Airborne particulate matter pollution has become a significant global health concern due to
its detrimental effects on human health, including cardiovascular diseases (CVDs) …

The association of airborne particulate matter exposure with the deteriorating function of the
cardiovascular system is fundamentally driven by the impairment of mitochondrial-nuclear …

Air pollution has become an environmental burden with regard to non-communicable
diseases, particularly heart disease. It has been reported that air pollution can accelerate the …

Background Mitochondrial DNA copy number (mtCN) maintains cellular function and
homeostasis, and is linked to nuclear DNA methylation and gene expression. Increased …

Background Due to their lack of repair capacity mitochondria are critical targets for
environmental toxicants. We studied genes and pathways reflecting mitochondrial …

Mitochondrial (MT) dysfunction is a hallmark of aging and has been associated with most
aging-related diseases as well as immunological processes. However, little is known about …

The incidence rate of cardiovascular disease (CVD) has been increasing year by year and
has become the main cause for the increase of mortality. Mitochondrial DNA (mtDNA) plays …

Particulate matter (PM) air pollution exerts significant adverse health effects in global
populations, particularly in developing countries with extensive air pollution. Understanding …

Exposure to long-term ambient air pollution is believed to have adverse effects on human
health. However, the mechanisms underlying these impacts are poorly understood. DNA …

Importance Mitochondrial dysfunction is a core component of the aging process and may
play a key role in atherosclerotic cardiovascular disease. Mitochondrial DNA copy number …