Evidence suggests that psychopathology is associated with an advanced brain ageing
process, typically mapped using machine learning models that predict an individual's age …

Objective To evaluate whether accelerated brain aging occurs in individuals with mood or
psychotic disorders. Methods A systematic review following PRISMA guidelines was …

The deviation between chronological age and age predicted using brain MRI is a putative
marker of overall brain health. Age prediction based on structural MRI data shows high …

Conceptualizing mental disorders as deviations from normative functioning provides a
statistical perspective for understanding the individual heterogeneity underlying psychiatric …

Depression and anxiety are common and often comorbid mental health disorders that
represent risk factors for aging-related conditions. Brain aging has shown to be more …

Molecular biological findings indicate that affective disorders are associated with processes
akin to accelerated aging of the brain. The use of the BrainAGE (brain age estimation gap) …

Background Brain age is a popular brain-based biomarker that offers a powerful strategy for
using neuroscience in clinical practice. We investigated the brain-predicted age difference …

Background This study aimed to investigate whether dimensional constructs of
psychopathology relate to variation in patterns of brain development and to determine …

Problem: Chronological aging in later life is associated with brain degeneration processes
and increased risk for disease such as stroke and dementia. With a worldwide tendency of …

Structural brain abnormalities are central to schizophrenia (SZ), but it remains unknown
whether they are linked to dysmaturational processes crossing diagnostic boundaries …